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mapk8ip1b mitogen-activated protein kinase 8 interacting protein 1b [ Danio rerio (zebrafish) ]

Gene ID: 100333948, updated on 2-Nov-2024

Summary

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Official Symbol
mapk8ip1bprovided by ZNC
Official Full Name
mitogen-activated protein kinase 8 interacting protein 1bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-170525-1
See related
AllianceGenome:ZFIN:ZDB-GENE-170525-1
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary
Predicted to enable kinase activity. Predicted to act upstream of or within phosphorylation and regulation of JNK cascade. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human MAPK8IP1 (mitogen-activated protein kinase 8 interacting protein 1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See mapk8ip1b in Genome Data Viewer
Location:
chromosome: 7
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (72588380..72610889, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (72128831..72150874)

Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene HECT domain E3 ubiquitin protein ligase 4 Neighboring gene uncharacterized LOC137496244 Neighboring gene mitochondrial ribosomal protein L21 Neighboring gene equilibrative nucleoside transporter 2 Neighboring gene multiple PDZ domain crumbs cell polarity complex component

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within phosphorylation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within regulation of JNK cascade IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
C-Jun-amino-terminal kinase-interacting protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007118.7 Reference GRCz11 Primary Assembly

    Range
    72588380..72610889 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009303667.4 → XP_009301942.1  C-Jun-amino-terminal kinase-interacting protein 1

    UniProtKB/TrEMBL
    A0A8M3AUR2
    Conserved Domains (2) summary
    cd11943
    Location:454 → 508
    SH3_JIP1; Src homology 3 domain of JNK-interacting protein 1
    cd01212
    Location:525 → 670
    PTB_JIP; JNK-interacting protein-like (JIP) Phosphotyrosine-binding (PTB) domain
Nucleotide Protein Strain
Heading Accession and Version

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