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gramd1bb GRAM domain containing 1Bb [ Danio rerio (zebrafish) ]

Gene ID: 100332318, updated on 2-Nov-2024

Summary

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Official Symbol
gramd1bbprovided by ZNC
Official Full Name
GRAM domain containing 1Bbprovided by ZNC
Primary source
ZFIN:ZDB-GENE-140106-106
See related
Ensembl:ENSDARG00000074258 AllianceGenome:ZFIN:ZDB-GENE-140106-106
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
gramd1b
Summary
Predicted to be located in endoplasmic reticulum membrane; organelle membrane contact site; and plasma membrane. Is expressed in hindbrain and otic vesicle. Orthologous to human GRAMD1B (GRAM domain containing 1B). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See gramd1bb in Genome Data Viewer
Location:
chromosome: 18
Exon count:
27
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 18 NC_007129.7 (46833628..47024494, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 18 NC_007129.6 (46841811..47053930, complement)

Chromosome 18 - NC_007129.7Genomic Context describing neighboring genes Neighboring gene dapper homolog 3 Neighboring gene complement C5a receptor 1 Neighboring gene uncharacterized LOC137488343 Neighboring gene CXADR like membrane protein b Neighboring gene uncharacterized LOC137488344

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Genetic loci associated with renal function measures and chronic kidney disease in children: the Pediatric Investigation for Genetic Factors Linked with Renal Progression Consortium. Wuttke M, et al. Nephrol Dial Transplant, 2016 Feb. PMID 26420894, Free PMC Article
  2. Identifying the Transcriptional Drivers of Metastasis Embedded within Localized Melanoma. Suresh S, et al. Cancer Discov, 2023 Jan 9. PMID 36259947, Free PMC Article
  3. Phenotypic Landscape of Schizophrenia-Associated Genes Defines Candidates and Their Shared Functions. Thyme SB, et al. Cell, 2019 Apr 4. PMID 30929901, Free PMC Article
  4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Component Evidence Code Pubs
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in organelle membrane contact site IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
GRAM domain-containing protein 1B; protein Aster-B
Names
GRAM domain containing 1B
zmp:0000001146

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007129.7 Reference GRCz11 Primary Assembly

    Range
    46833628..47024494 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021467918.2 → XP_021323593.1  protein Aster-B isoform X9

    UniProtKB/TrEMBL
    A0A8M9PAN1
    Related
    ENSDARP00000150642.1, ENSDART00000182754.1
    Conserved Domains (2) summary
    cd13220
    Location:277 → 370
    PH-GRAM_GRAMDC; GRAM domain-containing protein (GRAMDC) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
    pfam16016
    Location:553 → 701
    DUF4782; Domain of unknown function (DUF4782)

  2. XM_021467917.2 → XP_021323592.1  protein Aster-B isoform X8

    UniProtKB/TrEMBL
    A0A8M9P1K0
    Conserved Domains (2) summary
    cd13220
    Location:277 → 370
    PH-GRAM_GRAMDC; GRAM domain-containing protein (GRAMDC) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
    pfam16016
    Location:553 → 701
    DUF4782; Domain of unknown function (DUF4782)

  3. XM_017352142.3 → XP_017207631.1  protein Aster-B isoform X6

    UniProtKB/TrEMBL
    A0A8M6Z2U8

  4. XM_017352140.3 → XP_017207629.1  protein Aster-B isoform X4

    UniProtKB/TrEMBL
    A0A8M6YUD5

  5. XM_021467916.2 → XP_021323591.1  protein Aster-B isoform X7

    UniProtKB/TrEMBL
    A0A8M9PMT9
    Conserved Domains (2) summary
    cd13220
    Location:284 → 377
    PH-GRAM_GRAMDC; GRAM domain-containing protein (GRAMDC) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
    pfam16016
    Location:560 → 708
    DUF4782; Domain of unknown function (DUF4782)

  6. XM_017352141.3 → XP_017207630.1  protein Aster-B isoform X5

    UniProtKB/TrEMBL
    A0A8M6YW88

  7. XM_017352138.3 → XP_017207627.1  protein Aster-B isoform X3

    UniProtKB/TrEMBL
    A0A8M6Z276

  8. XM_017352135.3 → XP_017207624.1  protein Aster-B isoform X1

    UniProtKB/TrEMBL
    A0A8M6YTR6

  9. XM_021467912.2 → XP_021323587.1  protein Aster-B isoform X2

    UniProtKB/TrEMBL
    A0A8M9P1J5
    Conserved Domains (2) summary
    cd13220
    Location:300 → 393
    PH-GRAM_GRAMDC; GRAM domain-containing protein (GRAMDC) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
    pfam16016
    Location:576 → 724
    DUF4782; Domain of unknown function (DUF4782)
Nucleotide Protein Strain
Heading Accession and Version

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