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hmox2b heme oxygenase 2b [ Danio rerio (zebrafish) ]

Gene ID: 100329531, updated on 2-Nov-2024

Summary

Official Symbol
hmox2bprovided by ZNC
Official Full Name
heme oxygenase 2bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-091118-52
See related
Ensembl:ENSDARG00000078452 AllianceGenome:ZFIN:ZDB-GENE-091118-52
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
si:dkey-254e1.2
Summary
Predicted to enable heme binding activity and heme oxygenase (decyclizing) activity. Predicted to be involved in heme catabolic process; heme oxidation; and response to oxidative stress. Predicted to be located in membrane. Is expressed in brain; gill; and liver. Orthologous to human HMOX2 (heme oxygenase 2). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See hmox2b in Genome Data Viewer
Location:
chromosome: 3
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (11956409..11972565, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (12016751..12032636, complement)

Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene coronin-7-like Neighboring gene DnaJ heat shock protein family (Hsp40) member A3a Neighboring gene cilia and flagella associated protein 70 Neighboring gene tubulin epsilon and delta complex 2

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables heme binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables heme oxygenase (decyclizing) activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables heme oxygenase (decyclizing) activity IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in heme catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in heme oxidation IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within heme oxidation IEA
Inferred from Electronic Annotation
more info
 
involved_in response to oxidative stress IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
heme oxygenase 2
Names
heme oxygenase (decycling) 2b

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007114.7 Reference GRCz11 Primary Assembly

    Range
    11956409..11972565 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021473067.2XP_021328742.1  heme oxygenase 2

    UniProtKB/TrEMBL
    A0A8M9PJ88, E7F079
    Related
    ENSDARP00000104304.2, ENSDART00000112800.5
    Conserved Domains (1) summary
    pfam01126
    Location:35240
    Heme_oxygenase; Heme oxygenase

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394520.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    87187..145687 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002661099.6XP_002661145.1  heme oxygenase 2

    See identical proteins and their annotated locations for XP_002661145.1

    UniProtKB/TrEMBL
    A0A8M9PJ88, E7F079
    Conserved Domains (1) summary
    pfam01126
    Location:35240
    Heme_oxygenase; Heme oxygenase
  2. XM_005168472.5XP_005168529.1  heme oxygenase 2

    See identical proteins and their annotated locations for XP_005168529.1

    UniProtKB/TrEMBL
    A0A8M9PJ88, E7F079
    Conserved Domains (1) summary
    pfam01126
    Location:35240
    Heme_oxygenase; Heme oxygenase
  3. XM_021471363.2XP_021327038.1  heme oxygenase 2

    UniProtKB/TrEMBL
    A0A8M9PJ88, E7F079
    Conserved Domains (1) summary
    pfam01126
    Location:35240
    Heme_oxygenase; Heme oxygenase