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st6galnac6 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 100329192, updated on 14-Nov-2024

Summary

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Official Symbol
st6galnac6provided by Xenbase
Official Full Name
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6provided by Xenbase
Primary source
Xenbase:XB-GENE-1012034
See related
Ensembl:ENSXETG00000021997 AllianceGenome:Xenbase:XB-GENE-1012034
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as
siat7f; st6galnacvi
Summary
Predicted to enable sialyltransferase activity. Predicted to act upstream of or within lipid metabolic process and protein glycosylation. Predicted to be located in Golgi apparatus and membrane. Orthologous to human ST6GALNAC6 (ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See st6galnac6 in Genome Data Viewer
Location:
chromosome: 8
Exon count:
9
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 8 NC_030684.2 (24382654..24402746)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 8 NC_030684.1 (2515701..2531926, complement)

Chromosome 8 - NC_030684.2Genomic Context describing neighboring genes Neighboring gene phosphatidylinositol-4-phosphate 5-kinase-like 1 Neighboring gene ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 Neighboring gene adenylate kinase 1 Neighboring gene endoglin

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables sialyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in ganglioside biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within lipid metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in oligosaccharide metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within protein glycosylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
  
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
Names
alpha-2,6-sialyltransferase
NP_001165302.1
XP_012823590.1
XP_012823592.1
XP_031746124.1
XP_031746125.1
XP_031746126.1
XP_031746127.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001171831.1 → NP_001165302.1  alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6

    See identical proteins and their annotated locations for NP_001165302.1

    Status: PROVISIONAL

    Source sequence(s)
    FN550109
    UniProtKB/TrEMBL
    A0A6I8PVP9, D2U4U3
    Related
    ENSXETP00000095239.1, ENSXETT00000105024.2
    Conserved Domains (1) summary
    pfam00777
    Location:68 → 261
    Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030684.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    24382654..24402746
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_031890267.1 → XP_031746127.1  alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 isoform X3

    UniProtKB/TrEMBL
    A0A6I8PVP9, A0A8J1IL02
    Conserved Domains (1) summary
    pfam00777
    Location:68 → 251
    Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

  2. XM_031890265.1 → XP_031746125.1  alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 isoform X2

    UniProtKB/TrEMBL
    A0A6I8PVP9, A0A803JLE8
    Conserved Domains (1) summary
    pfam00777
    Location:77 → 260
    Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

  3. XM_012968138.2 → XP_012823592.1  alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 isoform X3

    See identical proteins and their annotated locations for XP_012823592.1

    UniProtKB/TrEMBL
    A0A6I8PVP9, A0A8J1IL02
    Conserved Domains (1) summary
    pfam00777
    Location:68 → 251
    Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

  4. XM_031890264.1 → XP_031746124.1  alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 isoform X1

    UniProtKB/TrEMBL
    A0A6I8PVP9, F6PR61
    Related
    ENSXETP00000047609.4, ENSXETT00000047609.4
    Conserved Domains (1) summary
    pfam00777
    Location:109 → 292
    Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

  5. XM_012968136.2 → XP_012823590.1  alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 isoform X2

    See identical proteins and their annotated locations for XP_012823590.1

    UniProtKB/TrEMBL
    A0A6I8PVP9, A0A803JLE8
    Related
    ENSXETP00000108746.1, ENSXETT00000119952.1
    Conserved Domains (1) summary
    pfam00777
    Location:77 → 260
    Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

  6. XM_031890266.1 → XP_031746126.1  alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 isoform X3

    UniProtKB/TrEMBL
    A0A6I8PVP9, A0A8J1IL02
    Conserved Domains (1) summary
    pfam00777
    Location:68 → 251
    Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)
Nucleotide Protein Strain
Heading Accession and Version

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