st3gal5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 [Xenopus tropicalis (tropical clawed frog)] - Gene

Summary

Official Symbol: st3gal5provided by Xenbase
Official Full Name: ST3 beta-galactoside alpha-2,3-sialyltransferase 5provided by Xenbase
Primary source: Xenbase:XB-GENE-955106
See related: AllianceGenome:Xenbase:XB-GENE-955106
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus tropicalis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Summary: Predicted to enable sialyltransferase activity. Predicted to act upstream of or within protein glycosylation. Predicted to be located in Golgi membrane. Human ortholog(s) of this gene implicated in salt and pepper syndrome. Orthologous to human ST3GAL5 (ST3 beta-galactoside alpha-2,3-sialyltransferase 5). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
104	current	UCB_Xtro_10.0 (GCF_000004195.4)	1	NC_030677.2 (18581655..18611237)
103	previous assembly	Xenopus_tropicalis_v9.1 (GCF_000004195.3)	1	NC_030677.1 (15029746..15061294, complement)

Chromosome 1 - NC_030677.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables glycosyltransferase activity	IEA Inferred from Electronic Annotation more info
enables lactosylceramide alpha-2,3-sialyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables sialyltransferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within lipid metabolic process	IEA Inferred from Electronic Annotation more info
involved_in protein glycosylation	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within protein glycosylation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in Golgi apparatus	IEA Inferred from Electronic Annotation more info
located_in Golgi membrane	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: lactosylceramide alpha-2,3-sialyltransferase

Names: alpha-2,3-sialyltransferase

NP_001165301.1

EC 2.4.3.9

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001171830.1 → NP_001165301.1 lactosylceramide alpha-2,3-sialyltransferase

See identical proteins and their annotated locations for NP_001165301.1

Status: PROVISIONAL

Source sequence(s)

FN550108

UniProtKB/TrEMBL

D2U4U2, F6YHB1

Conserved Domains (1) summary

pfam00777
Location:89 → 356

Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)