tac3a tachykinin precursor 3a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: tac3aprovided by ZNC
Official Full Name: tachykinin precursor 3aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-090313-253
See related: Ensembl:ENSDARG00000093089 AllianceGenome:ZFIN:ZDB-GENE-090313-253
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: tac2a; si:dkey-228g21.4
Summary: Predicted to be involved in positive regulation of blood pressure. Predicted to act upstream of or within tachykinin receptor signaling pathway. Predicted to be located in extracellular region. Is expressed in several structures, including adipose tissue; liver; male organism; nervous system; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 10 with or without anosmia. Orthologous to human TAC3 (tachykinin precursor 3). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 23

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	23	NC_007134.7 (28139322..28141434, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	23	NC_007134.6 (28212774..28214877, complement)

Chromosome 23 - NC_007134.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Knockout of tac3 genes in zebrafish shows no impairment of reproduction.
Title: Knockout of tac3 genes in zebrafish shows no impairment of reproduction.
The full-length cDNA sequences encoding multiple TAC3s (TAC3a and TAC3b) and TACR3s (TACR3a1, TACR3a2 and TACR3b) were cloned from zebrafish brain samples.
Title: The evolution of tachykinin/tachykinin receptor (TAC/TACR) in vertebrates and molecular identification of the TAC3/TACR3 system in zebrafish (Danio rerio).

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General gene information

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Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
involved_in positive regulation of blood pressure	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within tachykinin receptor signaling pathway	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: tachykinin-3a

Names: neurokinin B; preprotachykinin 2a; tachykinin 3a

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.