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MIR509A-2 microRNA mir-509a-2 [ Pan troglodytes (chimpanzee) ]

Gene ID: 100316418, updated on 29-Mar-2024

Summary

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Gene symbol
MIR509A-2
Gene description
microRNA mir-509a-2
See related
miRBase:MI0006627
Gene type
ncRNA
RefSeq status
PROVISIONAL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Also known as
ptr-mir-509a-2
Summary
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Annotation information
not in current annotation release
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Genomic context

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See MIR509A-2 in Genome Data Viewer
Location:
chromosome: X
Annotation release Status Assembly Chr Location
RS_2023_03 latest, but not current NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) X NC_072421.1 (144653266..144653359, complement)

Bibliography

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Related articles in PubMed

  1. Rapid evolution of an X-linked microRNA cluster in primates. Zhang R, et al. Genome Res, 2007 May. PMID 17416744, Free PMC Article
  2. miRBase: microRNA sequences, targets and gene nomenclature. Griffiths-Jones S, et al. Nucleic Acids Res, 2006 Jan 1. PMID 16381832, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Other Names

  • microRNA 509a-2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_035537.1 RNA Sequence

    Status: PROVISIONAL

    Source sequence(s)
    NBAG03000467

Gene LinkOut

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