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Mir34 microRNA mir-34 [ Strongylocentrotus purpuratus (purple sea urchin) ]

Gene ID: 100314401, updated on 7-Nov-2020

Summary

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Gene symbol
Mir34
Gene description
microRNA mir-34
See related
miRBase:MI0010195
Gene type
ncRNA
RefSeq status
PROVISIONAL
Organism
Strongylocentrotus purpuratus
Lineage
Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Echinoidea; Euechinoidea; Echinacea; Camarodonta; Echinidea; Strongylocentrotidae; Strongylocentrotus
Also known as
mir-34; spu-mir-34
Summary
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
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Genomic context

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See Mir34 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
1
Annotation release Status Assembly Chr Location
102 current Spur_5.0 (GCF_000002235.5) Unplaced Scaffold NW_022145594.1 (43627743..43627843, complement)
Build 3.1 previous assembly Spur_3.1 (GCF_000002235.3) Unplaced Scaffold NW_003577000.1 (164281..164381, complement)

NW_022145594.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 192 Neighboring gene UPF0722 protein Neighboring gene RNA polymerase II subunit H Neighboring gene microRNA mir-2002 Neighboring gene cytochrome P450 3A6

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The deep evolution of metazoan microRNAs. Wheeler BM, et al. Evol Dev, 2009 Jan-Feb. PMID 19196333
  2. miRBase: integrating microRNA annotation and deep-sequencing data. Kozomara A, et al. Nucleic Acids Res, 2011 Jan. PMID 21037258, Free PMC Article
  3. miRBase: microRNA sequences, targets and gene nomenclature. Griffiths-Jones S, et al. Nucleic Acids Res, 2006 Jan 1. PMID 16381832, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Other Names

  • microRNA 34

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_036398.1 RNA Sequence

    Status: PROVISIONAL

    Source sequence(s)
    AAGJ06000001

RefSeqs of Annotated Genomes: Strongylocentrotus purpuratus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Spur_5.0 Primary Assembly

Genomic

  1. NW_022145594.1 Reference Spur_5.0 Primary Assembly

    Range
    43627743..43627843 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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