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hnrnpab.S heterogeneous nuclear ribonucleoprotein A/B S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 100302093, updated on 4-Nov-2024

Summary

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Official Symbol
hnrnpab.S
Official Full Name
heterogeneous nuclear ribonucleoprotein A/B S homeolog
Primary source
Xenbase:XB-GENE-17331791
Locus tag
XELAEV_18021534mg
See related
EnsemblRapid:ENSXLAG00005004602 AllianceGenome:Xenbase:XB-GENE-17331791
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
40LoVe
Summary
Predicted to enable RNA binding activity. Predicted to act upstream of or within positive regulation of macromolecule biosynthetic process; regulation of RNA metabolic process; and regulation of gene expression. Predicted to be located in cytoplasm and nucleoplasm. Predicted to be part of ribonucleoprotein complex. Human ortholog(s) of this gene implicated in hepatocellular carcinoma. Orthologous to human HNRNPAB (heterogeneous nuclear ribonucleoprotein A/B). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See hnrnpab.S in Genome Data Viewer
Location:
chromosome: 3S
Exon count:
10
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 3S NC_054376.1 (115978931..115990638, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 3S NC_030729.1 (114096188..114107895, complement)

Chromosome 3S - NC_054376.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108713292 Neighboring gene heterogeneous nuclear ribonucleoprotein A0 S homeolog Neighboring gene purine-rich element binding protein A L homeolog Neighboring gene matrin 3 S homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Interactions of 40LoVe within the ribonucleoprotein complex that forms on the localization element of Xenopus Vg1 mRNA. Kroll TT, et al. Mech Dev, 2009 Jul. PMID 19345262
  2. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC83385

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within positive regulation of macromolecule biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within regulation of RNA metabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within regulation of gene expression IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
heterogeneous nuclear ribonucleoprotein A/B S homeolog
Names
CArG-binding factor A
Vg1 mRNA binding protein 40

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001161893.1 → NP_001155365.1  heterogeneous nuclear ribonucleoprotein A/B S homeolog

    See identical proteins and their annotated locations for NP_001155365.1

    Status: PROVISIONAL

    Source sequence(s)
    EU003449
    UniProtKB/TrEMBL
    A0A974DAK5, Q6GM69
    Related
    ENSXLAP00005013771.1, ENSXLAT00005013954.1
    Conserved Domains (3) summary
    pfam08143
    Location:1 → 52
    CBFNT; CBFNT (NUC161) domain
    cd12584
    Location:145 → 224
    RRM2_hnRNPAB; RNA recognition motif 2 (RRM2) found in heterogeneous nuclear ribonucleoprotein A/B (hnRNP A/B) and similar proteins
    cd12757
    Location:61 → 140
    RRM1_hnRNPAB; RNA recognition motif 1 (RRM1) found in heterogeneous nuclear ribonucleoprotein A/B (hnRNP A/B) and similar proteins

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054376.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    115978931..115990638 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018254004.1 → XP_018109493.1  heterogeneous nuclear ribonucleoprotein A/B S homeolog isoform X1

    UniProtKB/TrEMBL
    A0A974DAK5, Q6GM69
    Conserved Domains (3) summary
    pfam08143
    Location:1 → 52
    CBFNT; CBFNT (NUC161) domain
    cd12584
    Location:145 → 224
    RRM2_hnRNPAB; RNA recognition motif 2 (RRM2) found in heterogeneous nuclear ribonucleoprotein A/B (hnRNP A/B) and similar proteins
    cd12757
    Location:61 → 140
    RRM1_hnRNPAB; RNA recognition motif 1 (RRM1) found in heterogeneous nuclear ribonucleoprotein A/B (hnRNP A/B) and similar proteins

  2. XM_018254003.1 → XP_018109492.1  heterogeneous nuclear ribonucleoprotein A/B S homeolog isoform X1

    UniProtKB/TrEMBL
    A0A974DAK5, Q6GM69
    Related
    ENSXLAP00005013780.1, ENSXLAT00005013962.1
    Conserved Domains (3) summary
    pfam08143
    Location:1 → 52
    CBFNT; CBFNT (NUC161) domain
    cd12584
    Location:145 → 224
    RRM2_hnRNPAB; RNA recognition motif 2 (RRM2) found in heterogeneous nuclear ribonucleoprotein A/B (hnRNP A/B) and similar proteins
    cd12757
    Location:61 → 140
    RRM1_hnRNPAB; RNA recognition motif 1 (RRM1) found in heterogeneous nuclear ribonucleoprotein A/B (hnRNP A/B) and similar proteins

  3. XM_018254005.2 → XP_018109494.1  heterogeneous nuclear ribonucleoprotein A/B S homeolog isoform X2

    UniProtKB/TrEMBL
    A0A8J1MNQ4
    Related
    ENSXLAP00005013788.1, ENSXLAT00005013970.1
    Conserved Domains (3) summary
    pfam08143
    Location:1 → 52
    CBFNT; CBFNT (NUC161) domain
    cd12584
    Location:132 → 211
    RRM2_hnRNPAB; RNA recognition motif 2 (RRM2) found in heterogeneous nuclear ribonucleoprotein A/B (hnRNP A/B) and similar proteins
    cd12757
    Location:48 → 127
    RRM1_hnRNPAB; RNA recognition motif 1 (RRM1) found in heterogeneous nuclear ribonucleoprotein A/B (hnRNP A/B) and similar proteins

  4. XM_041587480.1 → XP_041443414.1  heterogeneous nuclear ribonucleoprotein A/B S homeolog isoform X2

    UniProtKB/TrEMBL
    A0A8J1MNQ4
    Conserved Domains (3) summary
    pfam08143
    Location:1 → 52
    CBFNT; CBFNT (NUC161) domain
    cd12584
    Location:132 → 211
    RRM2_hnRNPAB; RNA recognition motif 2 (RRM2) found in heterogeneous nuclear ribonucleoprotein A/B (hnRNP A/B) and similar proteins
    cd12757
    Location:48 → 127
    RRM1_hnRNPAB; RNA recognition motif 1 (RRM1) found in heterogeneous nuclear ribonucleoprotein A/B (hnRNP A/B) and similar proteins

  5. XM_041587477.1 → XP_041443411.1  heterogeneous nuclear ribonucleoprotein A/B S homeolog isoform X1

    UniProtKB/TrEMBL
    A0A974DAK5, Q6GM69
    Conserved Domains (3) summary
    pfam08143
    Location:1 → 52
    CBFNT; CBFNT (NUC161) domain
    cd12584
    Location:145 → 224
    RRM2_hnRNPAB; RNA recognition motif 2 (RRM2) found in heterogeneous nuclear ribonucleoprotein A/B (hnRNP A/B) and similar proteins
    cd12757
    Location:61 → 140
    RRM1_hnRNPAB; RNA recognition motif 1 (RRM1) found in heterogeneous nuclear ribonucleoprotein A/B (hnRNP A/B) and similar proteins

  6. XM_041587479.1 → XP_041443413.1  heterogeneous nuclear ribonucleoprotein A/B S homeolog isoform X1

    UniProtKB/TrEMBL
    A0A974DAK5, Q6GM69
    Conserved Domains (3) summary
    pfam08143
    Location:1 → 52
    CBFNT; CBFNT (NUC161) domain
    cd12584
    Location:145 → 224
    RRM2_hnRNPAB; RNA recognition motif 2 (RRM2) found in heterogeneous nuclear ribonucleoprotein A/B (hnRNP A/B) and similar proteins
    cd12757
    Location:61 → 140
    RRM1_hnRNPAB; RNA recognition motif 1 (RRM1) found in heterogeneous nuclear ribonucleoprotein A/B (hnRNP A/B) and similar proteins
Nucleotide Protein Strain
Heading Accession and Version

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