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hagh hydroxyacylglutathione hydrolase [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 100216043, updated on 17-Aug-2024

Summary

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Official Symbol
haghprovided by Xenbase
Official Full Name
hydroxyacylglutathione hydrolaseprovided by Xenbase
Primary source
Xenbase:XB-GENE-966712
See related
Ensembl:ENSXETG00000007202
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as
glo2; glx2; glo-2; glxii; hagh1
Orthologs
human mouse all
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Genomic context

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See hagh in Genome Data Viewer
Location:
chromosome: 9
Exon count:
16
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 9 NC_030685.2 (16670609..16684832)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 9 NC_030685.1 (10873945..10879623)

Chromosome 9 - NC_030685.2Genomic Context describing neighboring genes Neighboring gene cytosolic iron-sulfur assembly component 3 Neighboring gene hydroxyacylglutathione hydrolase like Neighboring gene fumarylacetoacetate hydrolase domain containing 1 Neighboring gene meiosis specific with OB domains

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables hydroxyacylglutathione hydrolase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables hydroxyacylglutathione hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables hydroxyacylglutathione hydrolase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in glutathione metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrial matrix IEA
Inferred from Electronic Annotation
more info
  
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
hydroxyacylglutathione hydrolase, mitochondrial
Names
Glx II
glyoxalase II
NP_001135503.1
XP_031748407.1
XP_031748408.1
XP_031748409.1
XP_031748410.1
XP_031748411.1
XP_031748412.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001142031.1 → NP_001135503.1  hydroxyacylglutathione hydrolase, mitochondrial precursor

    See identical proteins and their annotated locations for NP_001135503.1

    Status: PROVISIONAL

    Source sequence(s)
    BC167912
    UniProtKB/Swiss-Prot
    B4F6K2
    UniProtKB/TrEMBL
    A0A6I8SCH8
    Conserved Domains (1) summary
    PLN02469
    Location:54 → 309
    PLN02469; hydroxyacylglutathione hydrolase

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030685.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    16670609..16684832
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_031892549.1 → XP_031748409.1  hydroxyacylglutathione hydrolase, mitochondrial isoform X3

    UniProtKB/TrEMBL
    A0A6I8Q7B6, A0A6I8SCH8
    Related
    ENSXETP00000068412.2, ENSXETT00000085763.2
    Conserved Domains (1) summary
    PLN02469
    Location:54 → 309
    PLN02469; hydroxyacylglutathione hydrolase

  2. XM_031892551.1 → XP_031748411.1  hydroxyacylglutathione hydrolase, mitochondrial isoform X4

    UniProtKB/TrEMBL
    A0A8J1IUH4
    Conserved Domains (1) summary
    PLN02469
    Location:1 → 256
    PLN02469; hydroxyacylglutathione hydrolase

  3. XM_031892547.1 → XP_031748407.1  hydroxyacylglutathione hydrolase, mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A6I8SCH8, G1K3C6
    Related
    ENSXETP00000015653.5, ENSXETT00000015653.5
    Conserved Domains (1) summary
    PLN02469
    Location:72 → 327
    PLN02469; hydroxyacylglutathione hydrolase

  4. XM_031892550.1 → XP_031748410.1  hydroxyacylglutathione hydrolase, mitochondrial isoform X4

    UniProtKB/TrEMBL
    A0A8J1IUH4
    Conserved Domains (1) summary
    PLN02469
    Location:1 → 256
    PLN02469; hydroxyacylglutathione hydrolase

  5. XM_031892548.1 → XP_031748408.1  hydroxyacylglutathione hydrolase, mitochondrial isoform X2

    UniProtKB/TrEMBL
    A0A6I8SCH8, A0A8J1IS34
    Related
    ENSXETP00000090266.2, ENSXETT00000086871.2
    Conserved Domains (1) summary
    PLN02469
    Location:72 → 327
    PLN02469; hydroxyacylglutathione hydrolase

  6. XM_031892552.1 → XP_031748412.1  hydroxyacylglutathione hydrolase, mitochondrial isoform X4

    UniProtKB/TrEMBL
    A0A8J1IUH4
    Conserved Domains (1) summary
    PLN02469
    Location:1 → 256
    PLN02469; hydroxyacylglutathione hydrolase
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
B4F6K2.1 GenPept UniProtKB/Swiss-Prot:B4F6K2

Gene LinkOut

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