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Cacnb2 calcium voltage-gated channel auxiliary subunit beta 2 [ Cavia porcellus (domestic guinea pig) ]

Gene ID: 100192393, updated on 10-Oct-2024

Summary

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Gene symbol
Cacnb2
Gene description
calcium voltage-gated channel auxiliary subunit beta 2
See related
Ensembl:ENSCPOG00000005845
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Cavia porcellus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae; Cavia
Orthologs
human mouse all
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Genomic context

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See Cacnb2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
21
Annotation release Status Assembly Chr Location
RS_2024_02 current mCavPor4.1 (GCF_034190915.1) Unplaced Scaffold NW_026947510.1 (11326593..11668924)
103 previous assembly Cavpor3.0 (GCF_000151735.1) Unplaced Scaffold NT_176299.1 (477494..823694, complement)

NW_026947510.1Genomic Context describing neighboring genes Neighboring gene mannose receptor C-type 1 Neighboring gene solute carrier family 39 member 12 Neighboring gene uncharacterized LOC106025971 Neighboring gene E2F-associated phosphoprotein-like Neighboring gene uncharacterized LOC134473488 Neighboring gene uncharacterized LOC134473489 Neighboring gene proliferating cell nuclear antigen-like Neighboring gene small nucleolar RNA SNORA2/SNORA34 family Neighboring gene uncharacterized LOC134473604 Neighboring gene RAB43, member RAS oncogene family

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Gestational changes in uterine L-type calcium channel function and expression in guinea pig. Collins PL, et al. Biol Reprod, 2000 Nov. PMID 11058528
  2. Cloning and expression of the Ca2+ channel alpha1C and beta2a subunits from guinea pig heart. Ding S, et al. J Biochem, 1999 Apr. PMID 10101289

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables voltage-gated calcium channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in calcium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of voltage-gated calcium channel complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
voltage-dependent L-type calcium channel subunit beta-2
Names
L-type calcium channel beta subunit
calcium channel, voltage-dependent, beta 2 subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001173051.1 → NP_001166522.1  voltage-dependent L-type calcium channel subunit beta-2

    See identical proteins and their annotated locations for NP_001166522.1

    Status: PROVISIONAL

    Source sequence(s)
    AB016288
    UniProtKB/TrEMBL
    H0V6F4, Q9QWL3
    Related
    ENSCPOP00000005273.3, ENSCPOT00000005908.3
    Conserved Domains (4) summary
    cd12040
    Location:58 → 126
    SH3_CACNB2; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta2
    pfam00625
    Location:226 → 406
    Guanylate_kin; Guanylate kinase
    pfam12052
    Location:18 → 59
    VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal
    cl17190
    Location:236 → 407
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

RefSeqs of Annotated Genomes: GCF_034190915.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mCavPor4.1

Genomic

  1. NW_026947510.1 Reference mCavPor4.1

    Range
    11326593..11668924
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063237565.1 → XP_063093635.1  voltage-dependent L-type calcium channel subunit beta-2 isoform X3

  2. XM_063237564.1 → XP_063093634.1  voltage-dependent L-type calcium channel subunit beta-2 isoform X1

  3. XM_013144540.3 → XP_012999994.1  voltage-dependent L-type calcium channel subunit beta-2 isoform X8

    UniProtKB/TrEMBL
    H0V6F4
    Conserved Domains (4) summary
    cd12040
    Location:84 → 152
    SH3_CACNB2; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta2
    pfam00625
    Location:214 → 394
    Guanylate_kin; Guanylate kinase
    pfam12052
    Location:44 → 85
    VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal
    cl17190
    Location:224 → 395
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

  4. XM_013144538.3 → XP_012999992.1  voltage-dependent L-type calcium channel subunit beta-2 isoform X2

    UniProtKB/TrEMBL
    H0V6F4
    Conserved Domains (4) summary
    cd12040
    Location:84 → 152
    SH3_CACNB2; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta2
    pfam00625
    Location:252 → 432
    Guanylate_kin; Guanylate kinase
    pfam12052
    Location:44 → 85
    VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal
    cl17190
    Location:262 → 433
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

  5. XM_063237566.1 → XP_063093636.1  voltage-dependent L-type calcium channel subunit beta-2 isoform X6

  6. XM_063237568.1 → XP_063093638.1  voltage-dependent L-type calcium channel subunit beta-2 isoform X7

  7. XM_013144539.3 → XP_012999993.1  voltage-dependent L-type calcium channel subunit beta-2 isoform X5

    UniProtKB/TrEMBL
    A0A286XSF8, H0V6F4
    Related
    ENSCPOP00000028461.1
    Conserved Domains (4) summary
    cd12040
    Location:58 → 126
    SH3_CACNB2; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta2
    pfam00625
    Location:226 → 406
    Guanylate_kin; Guanylate kinase
    pfam12052
    Location:18 → 59
    VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal
    cl17190
    Location:236 → 407
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

  8. XM_063237569.1 → XP_063093639.1  voltage-dependent L-type calcium channel subunit beta-2 isoform X9

  9. XM_005000354.4 → XP_005000411.1  voltage-dependent L-type calcium channel subunit beta-2 isoform X4

    UniProtKB/TrEMBL
    A0A286Y2M4, H0V6F4
    Related
    ENSCPOP00000031770.1
    Conserved Domains (4) summary
    cd12040
    Location:64 → 132
    SH3_CACNB2; Src Homology 3 domain of Voltage-dependent L-type calcium channel subunit beta2
    pfam00625
    Location:232 → 412
    Guanylate_kin; Guanylate kinase
    pfam12052
    Location:24 → 65
    VGCC_beta4Aa_N; Voltage gated calcium channel subunit beta domain 4Aa N terminal
    cl17190
    Location:242 → 413
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

  10. XM_013144541.3 → XP_012999995.2  voltage-dependent L-type calcium channel subunit beta-2 isoform X10

Nucleotide Protein
Heading Accession and Version

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