ephb4.L EPH receptor B4 L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: ephb4.L
Official Full Name: EPH receptor B4 L homeolog
Primary source: Xenbase:XB-GENE-6251588
Locus tag: XELAEV_18019575mg
See related: EnsemblRapid:ENSXLAG00005022635
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: G51; htk; myk1; ephb4; ephb4b; tyro11; ephb4-a; ephb4-b
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Genomic context

Location:: chromosome: 3L

Exon count:: 16

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	3L	NC_054375.1 (159718902..159745466)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	3L	NC_030728.1 (142657255..142681910)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	Unplaced Scaffold	NW_016713071.1 (107..754)

Chromosome 3L - NC_054375.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables ephrin receptor activity	IEA Inferred from Electronic Annotation more info
enables protein tyrosine kinase activity	IEA Inferred from Electronic Annotation more info
enables transmembrane receptor protein tyrosine kinase activity	IEA Inferred from Electronic Annotation more info
enables transmembrane-ephrin receptor activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within axon guidance	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within cell surface receptor protein tyrosine kinase signaling pathway	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within ephrin receptor signaling pathway	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within nervous system development	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within protein phosphorylation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in dendrite	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: EPH receptor B4 L homeolog

Names: eph receptor tyrosine kinase

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001136172.2 → NP_001129644.1 EPH receptor B4 L homeolog precursor

See identical proteins and their annotated locations for NP_001129644.1

Status: PROVISIONAL

Source sequence(s)

BC108541

UniProtKB/TrEMBL

Q32NP2, Q6KF80

Related

ENSXLAP00005066643.1, ENSXLAT00005068167.1

Conserved Domains (8) summary

cd05065
Location:608 → 876

PTKc_EphR_B; Catalytic domain of the Protein Tyrosine Kinases, Class EphB Ephrin Receptors

cd09554
Location:905 → 971

SAM_EPH-B4; SAM domain of EPH-B4 subfamily of tyrosine kinase receptors

smart00454
Location:902 → 967

SAM; Sterile alpha motif

cd10474
Location:17 → 196

EphR_LBD_B4; Ligand Binding Domain of Ephrin type-B Receptor 4

cd00063
Location:324 → 425

FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

pfam00041
Location:432 → 517

fn3; Fibronectin type III domain

pfam07714
Location:613 → 872

Pkinase_Tyr; Protein tyrosine kinase

pfam14575
Location:545 → 608

EphA2_TM; Ephrin type-A receptor 2 transmembrane domain