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pcdh1.L protocadherin 1 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 100191020, updated on 4-Nov-2024

Summary

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Official Symbol
pcdh1.L
Official Full Name
protocadherin 1 L homeolog
Primary source
Xenbase:XB-GENE-983608
Locus tag
XELAEV_18017099mg
See related
AllianceGenome:Xenbase:XB-GENE-983608
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
axpc; pcdh1; PCDH-1
Summary
Is expressed in anatomical system and primary germ layer. Orthologous to human PCDH1 (protocadherin 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See pcdh1.L in Genome Data Viewer
Location:
chromosome: 3L
Exon count:
9
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 3L NC_054375.1 (36055477..36195889)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 3L NC_030728.1 (23149426..23290128)

Chromosome 3L - NC_054375.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108710894 Neighboring gene uncharacterized LOC121401158 Neighboring gene uncharacterized LOC108710895 Neighboring gene matrin 3 L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Axial protocadherin is a mediator of prenotochord cell sorting in Xenopus. Kuroda H, et al. Dev Biol, 2002 Apr 15. PMID 11944936
  2. Axial protocadherin (AXPC) regulates cell fate during notochordal morphogenesis. Yoder MD, et al. Dev Dyn, 2011 Nov. PMID 21960065, Free PMC Article
  3. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. AXPC functions in notochord morphogenesis by directing cell-fate decisions rather than cell-cell adhesion.
    Title: Axial protocadherin (AXPC) regulates cell fate during notochordal morphogenesis.
Submit: New GeneRIF Correction

General gene information

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Homology

Clone Names

  • MGC86208

General protein information

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Preferred Names
protocadherin 1 L homeolog; protocadherin-1
Names
axial protocadherin

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054375.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    36055477..36195889
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018250560.2 → XP_018106049.1  protocadherin-1 isoform X1

    UniProtKB/TrEMBL
    A0A1L8GX95, A0A974DDA8, Q6AX49

  2. XM_018250566.2 → XP_018106055.1  protocadherin-1 isoform X4

    UniProtKB/TrEMBL
    A0A8J0ULG9, Q6AX49

  3. XM_018250564.2 → XP_018106053.1  protocadherin-1 isoform X3

    UniProtKB/TrEMBL
    A0A8J0UES1, Q6AX49

  4. XM_041586139.1 → XP_041442073.1  protocadherin-1 isoform X2

    UniProtKB/TrEMBL
    A0A8J1MKR7, Q90ZF2
    Conserved Domains (2) summary
    cd11304
    Location:476 → 572
    Cadherin_repeat; Cadherin tandem repeat domain
    pfam08374
    Location:779 → 992
    Protocadherin

  5. XM_018250561.2 → XP_018106050.1  protocadherin-1 isoform X2

    UniProtKB/TrEMBL
    A0A8J1MKR7, Q90ZF2
    Conserved Domains (2) summary
    cd11304
    Location:476 → 572
    Cadherin_repeat; Cadherin tandem repeat domain
    pfam08374
    Location:779 → 992
    Protocadherin

  6. XM_018250562.2 → XP_018106051.1  protocadherin-1 isoform X2

    UniProtKB/TrEMBL
    A0A8J1MKR7, Q90ZF2
    Conserved Domains (2) summary
    cd11304
    Location:476 → 572
    Cadherin_repeat; Cadherin tandem repeat domain
    pfam08374
    Location:779 → 992
    Protocadherin

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001136169.1: Suppressed sequence

    Description
    NM_001136169.1: This RefSeq was removed because it is a nonsense-mediated mRNA decay (NMD) candidate.
Nucleotide Protein Strain
Heading Accession and Version

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