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mir219 microRNA mir-219 [ Ciona intestinalis (vase tunicate) ]

Gene ID: 100187679, updated on 28-Jan-2023

Summary

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Gene symbol
mir219
Gene description
microRNA mir-219
See related
miRBase:MI0007178
Gene type
ncRNA
RefSeq status
PROVISIONAL
Organism
Ciona intestinalis
Lineage
Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Phlebobranchia; Cionidae; Ciona
Also known as
mirn219; cin-mir-219
Summary
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
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Genomic context

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See mir219 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
1
Annotation release Status Assembly Chr Location
104 current KH (GCF_000224145.3) 7 NC_020172.2 (4343063..4343164)

Chromosome 7 - NC_020172.2Genomic Context describing neighboring genes Neighboring gene ankyrin-3-like Neighboring gene neutrophil cytosolic factor 2 Neighboring gene hemicentin-1 Neighboring gene U5 spliceosomal RNA Neighboring gene U5 spliceosomal RNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_020172.2 Chromosome 7 Reference KH Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Altered miRNA repertoire in the simplified chordate, Oikopleura dioica. Fu X, et al. Mol Biol Evol, 2008 Jun. PMID 18339653
  2. miRTRAP, a computational method for the systematic identification of miRNAs from high throughput sequencing data. Hendrix D, et al. Genome Biol, 2010. PMID 20370911, Free PMC Article
  3. miRBase: microRNA sequences, targets and gene nomenclature. Griffiths-Jones S, et al. Nucleic Acids Res, 2006 Jan 1. PMID 16381832, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Other Names

  • microRNA 219

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_032349.1 RNA Sequence

    Status: PROVISIONAL

    Source sequence(s)
    EAAA01002470

RefSeqs of Annotated Genomes: Ciona intestinalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference KH Primary Assembly

Genomic

  1. NC_020172.2 Reference KH Primary Assembly

    Range
    4343063..4343164
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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