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PTPRN protein tyrosine phosphatase receptor type N [ Pongo abelii (Sumatran orangutan) ]

Gene ID: 100172921, updated on 10-Oct-2024

Summary

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Gene symbol
PTPRN
Gene description
protein tyrosine phosphatase receptor type N
Locus tag
CR201_G0032373
See related
Ensembl:ENSPPYG00000013205
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Pongo abelii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pongo
Orthologs
human mouse all
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Genomic context

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See PTPRN in Genome Data Viewer
Location:
chromosome: 11
Exon count:
23
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPonAbe1-v2.0_pri (GCF_028885655.2) 11 NC_071996.2 (122713902..122733731, complement)
RS_2023_04 previous assembly NHGRI_mPonAbe1-v1.1-hic.freeze_pri (GCF_028885655.1) 2B NC_071987.1 (120070330..120090121, complement)

Chromosome 11 - NC_071996.2Genomic Context describing neighboring genes Neighboring gene tubulin alpha-1D chain-like Neighboring gene DnaJ heat shock protein family (Hsp40) member B2 Neighboring gene uncharacterized LOC129058135 Neighboring gene uncharacterized LOC129057889 Neighboring gene regulated endocrine specific protein 18 Neighboring gene aspartyl aminopeptidase Neighboring gene uncharacterized LOC129058136

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • DKFZp459I028

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein tyrosine phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in insulin secretion involved in cellular response to glucose stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein dephosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of secretion IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in secretory granule IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in synapse IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
receptor-type tyrosine-protein phosphatase-like N
NP_001125982.1
XP_024098709.2
XP_024098711.2
XP_024098712.2
XP_063568528.1
XP_063568529.1
XP_063568530.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001132510.1 → NP_001125982.1  receptor-type tyrosine-protein phosphatase-like N precursor

    See identical proteins and their annotated locations for NP_001125982.1

    Status: PROVISIONAL

    Source sequence(s)
    CR859509
    UniProtKB/TrEMBL
    A0A2J8TUI1, Q5R982
    Related
    ENSPPYP00000014754.2, ENSPPYT00000015351.2
    Conserved Domains (4) summary
    smart00194
    Location:709 → 968
    PTPc; Protein tyrosine phosphatase, catalytic domain
    cd00047
    Location:736 → 968
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    pfam11548
    Location:472 → 557
    Receptor_IA-2; Protein-tyrosine phosphatase receptor IA-2
    pfam14948
    Location:60 → 138
    RESP18; RESP18 domain

RefSeqs of Annotated Genomes: GCF_028885655.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

Genomic

  1. NC_071996.2 Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

    Range
    122713902..122733731 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063712459.1 → XP_063568529.1  receptor-type tyrosine-protein phosphatase-like N isoform X5

  2. XM_024242941.3 → XP_024098709.2  receptor-type tyrosine-protein phosphatase-like N isoform X1

  3. XM_063712458.1 → XP_063568528.1  receptor-type tyrosine-protein phosphatase-like N isoform X3

  4. XM_024242943.3 → XP_024098711.2  receptor-type tyrosine-protein phosphatase-like N isoform X4

  5. XM_063712460.1 → XP_063568530.1  receptor-type tyrosine-protein phosphatase-like N isoform X6

  6. XM_024242944.3 → XP_024098712.2  receptor-type tyrosine-protein phosphatase-like N isoform X2

Nucleotide Protein
Heading Accession and Version

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