NR3C2 nuclear receptor subfamily 3 group C member 2 [Pongo abelii (Sumatran orangutan)] - Gene

Summary

Gene symbol: NR3C2
Gene description: nuclear receptor subfamily 3 group C member 2
Locus tag: CR201_G0000090
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Pongo abelii
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pongo
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 3

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPonAbe1-v2.0_pri (GCF_028885655.2)	3	NC_071988.2 (170055219..170261921, complement)
RS_2023_04	previous assembly	NHGRI_mPonAbe1-v1.1-hic.freeze_pri (GCF_028885655.1)	4	NC_071989.1 (170092507..170299209, complement)

Chromosome 3 - NC_071988.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

SHGC-50219 (e-PCR)
- UniSTS:17444

SHGC-59557 (e-PCR)
- UniSTS:2866

SHGC-83211 (e-PCR)
- UniSTS:95795

NR3C2 (e-PCR)
- UniSTS:266087

SHGC4-1531 (e-PCR)
- UniSTS:25271

G34293 (e-PCR)
- UniSTS:37338

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables estrogen response element binding	IEA Inferred from Electronic Annotation more info	PubMed
enables nuclear receptor activity	IEA Inferred from Electronic Annotation more info	PubMed
enables zinc ion binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in nuclear receptor-mediated steroid hormone signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of chromatin	IEA Inferred from Electronic Annotation more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: mineralocorticoid receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001132477.1 → NP_001125949.1 mineralocorticoid receptor

See identical proteins and their annotated locations for NP_001125949.1

Status: PROVISIONAL

Source sequence(s)

CR859436

UniProtKB/TrEMBL

A0A8I5TFS1, Q5R9F2

Conserved Domains (1) summary

cl02596
Location:609 → 642

NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers

RefSeqs of Annotated Genomes: GCF_028885655.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

Genomic

NC_071988.2 Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

Range

170055219..170261921 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)