CBR1 carbonyl reductase 1 [Pongo abelii (Sumatran orangutan)] - Gene

Summary

Gene symbol: CBR1
Gene description: carbonyl reductase 1
Locus tag: CR201_G0029221
See related: Ensembl:ENSPPYG00000011399
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Pongo abelii
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pongo
Also known as: PG-9-KR
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 22

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPonAbe1-v2.0_pri (GCF_028885655.2)	22	NC_072007.2 (46376054..46379179)
RS_2023_04	previous assembly	NHGRI_mPonAbe1-v1.1-hic.freeze_pri (GCF_028885655.1)	21	NC_072006.1 (40566003..40569128)

Chromosome 22 - NC_072007.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

GDB:185176 (e-PCR)
- UniSTS:155431

RH17586 (e-PCR)
- UniSTS:45641

RH91556 (e-PCR)
- UniSTS:88193

CBR1_1984 (e-PCR)
- UniSTS:280476

SHGC-52102 (e-PCR)
- UniSTS:56292

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables carbonyl reductase (NADPH) activity	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: carbonyl reductase [NADPH] 1

Names: 15-hydroxyprostaglandin dehydrogenase; 20-beta-hydroxysteroid dehydrogenase; NADPH-dependent carbonyl reductase 1; alcohol dehydrogenase [NAD(P)+] CBR1; prostaglandin 9-ketoreductase; prostaglandin-E(2) 9-reductase

NP_001125206.1

EC 1.1.1.184

EC 1.1.1.189

EC 1.1.1.196

EC 1.1.1.197

EC 1.1.1.71

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001131734.1 → NP_001125206.1 carbonyl reductase [NADPH] 1

See identical proteins and their annotated locations for NP_001125206.1

Status: PROVISIONAL

Source sequence(s)

CR858173

UniProtKB/Swiss-Prot

Q5RCU5

UniProtKB/TrEMBL

A0A2J8UAC4, A0A8I5TKU0

Related

ENSPPYP00000026515.1, ENSPPYT00000055537.1

Conserved Domains (2) summary

cd05324
Location:6 → 277

carb_red_PTCR-like_SDR_c; Porcine testicular carbonyl reductase (PTCR)-like, classical (c) SDRs

pfam00106
Location:7 → 239

adh_short; short chain dehydrogenase