AGXT alanine--glyoxylate aminotransferase [Pongo abelii (Sumatran orangutan)] - Gene

Summary

Gene symbol: AGXT
Gene description: alanine--glyoxylate aminotransferase
Locus tag: CR201_G0049393
See related: Ensembl:ENSPPYG00000030682
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Pongo abelii
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pongo
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 11

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPonAbe1-v2.0_pri (GCF_028885655.2)	11	NC_071996.2 (144522738..144533703)
RS_2023_04	previous assembly	NHGRI_mPonAbe1-v1.1-hic.freeze_pri (GCF_028885655.1)	2B	NC_071987.1 (141879170..141890135)

Chromosome 11 - NC_071996.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables L-serine-pyruvate transaminase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables alanine-glyoxylate transaminase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in glycine biosynthetic process, by transamination of glyoxylate	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in peroxisome	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: alanine--glyoxylate aminotransferase

Names: AGT; SPT; Serine--pyruvate aminotransferase; alanine--glyoxylate and serine--pyruvate aminotransferase

NP_001125018.1

EC 2.6.1.44

EC 2.6.1.51

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001131546.1 → NP_001125018.1 alanine--glyoxylate aminotransferase

See identical proteins and their annotated locations for NP_001125018.1

Status: PROVISIONAL

Source sequence(s)

CR857864

UniProtKB/Swiss-Prot

Q5RDP0

Related

ENSPPYP00000033840.1, ENSPPYT00000036454.1

Conserved Domains (2) summary

cd06451
Location:24 → 385

AGAT_like; Alanine-glyoxylate aminotransferase (AGAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to alanine-glyoxylate aminotransferase (AGAT), ...

COG0075
Location:21 → 384

PucG; Archaeal aspartate aminotransferase or a related aminotransferase, includes purine catabolism protein PucG [Amino acid transport and metabolism, Nucleotide transport and metabolism]