ASAH1 N-acylsphingosine amidohydrolase 1 [Pongo abelii (Sumatran orangutan)] - Gene

Summary

Gene symbol: ASAH1
Gene description: N-acylsphingosine amidohydrolase 1
Locus tag: CR201_G0005052
See related: Ensembl:ENSPPYG00000018393
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Pongo abelii
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pongo
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 7

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPonAbe1-v2.0_pri (GCF_028885655.2)	7	NC_071992.2 (19822761..19850937, complement)
RS_2023_04	previous assembly	NHGRI_mPonAbe1-v1.1-hic.freeze_pri (GCF_028885655.1)	8	NC_071993.1 (21083855..21112600, complement)

Chromosome 7 - NC_071992.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Markers

D8S2114 (e-PCR)
- UniSTS:27209

D8S1586 (e-PCR)
- UniSTS:37707

D8S1341E (e-PCR)
- UniSTS:151161

SHGC-170029 (e-PCR)
- UniSTS:184819

RH94375 (e-PCR)
- UniSTS:87547

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables N-acylsphingosine amidohydrolase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables fatty acid amide hydrolase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in fatty acid metabolic process	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in lysosome	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: acid ceramidase

Names: N-acylsphingosine amidohydrolase (acid ceramidase) 1

NP_001124774.1

EC 3.5.1.23

XP_054416789.2

EC 3.5.1.23

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001131302.1 → NP_001124774.1 acid ceramidase precursor

See identical proteins and their annotated locations for NP_001124774.1

Status: PROVISIONAL

Source sequence(s)

CR857415

UniProtKB/TrEMBL

A0A2J8X474, A0A8I3B3C6, Q5R8N0, Q5RBU5, Q5REV1

Related

ENSPPYP00000037757.1, ENSPPYT00000057993.1

Conserved Domains (2) summary

cd01903
Location:134 → 379

Ntn_AC_NAAA; AC_NAAA This conserved domain includes two closely related proteins, acid ceramidase (AC, also known as N-acylsphingosine amidohydrolase), and N-acylethanolamine-hydrolyzing acid amidase (NAAA). AC catalyzes the hydrolysis of ceramide to sphingosine and ...

pfam15508
Location:45 → 139

NAAA-beta; beta subunit of N-acylethanolamine-hydrolyzing acid amidase

RefSeqs of Annotated Genomes: GCF_028885655.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

Genomic

NC_071992.2 Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

Range

19822761..19850937 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)