RHOA ras homolog family member A [Pongo abelii (Sumatran orangutan)] - Gene

Summary

Gene symbol: RHOA
Gene description: ras homolog family member A
Locus tag: CR201_G0035027
See related: Ensembl:ENSPPYG00000013873
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Pongo abelii
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pongo
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 2

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPonAbe1-v2.0_pri (GCF_028885655.2)	2	NC_085928.1 (105044708..105101356)
RS_2023_04	previous assembly	NHGRI_mPonAbe1-v1.1-hic.freeze_pri (GCF_028885655.1)	3	NC_071988.1 (92820548..92877707)

Chromosome 2 - NC_085928.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Markers

GDB:181197 (e-PCR)
- UniSTS:155171

D3S1330E (e-PCR)
- UniSTS:147343

A004T30 (e-PCR)
- UniSTS:72110

RH91501 (e-PCR)
- UniSTS:88496

WI-18922 (e-PCR)
- UniSTS:62388

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables GTP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables GTPase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables protein kinase binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in Rho protein signal transduction	IEA Inferred from Electronic Annotation more info	PubMed
involved_in stress fiber assembly	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cleavage furrow	IEA Inferred from Electronic Annotation more info	PubMed
located_in cytosol	IEA Inferred from Electronic Annotation more info	PubMed
located_in dendritic spine	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: transforming protein RhoA

Names: ras homolog gene family, member A

NP_001124755.1

EC 3.6.5.2

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001131283.2 → NP_001124755.1 transforming protein RhoA

See identical proteins and their annotated locations for NP_001124755.1

Status: PROVISIONAL

Source sequence(s)

CR857377

UniProtKB/Swiss-Prot

Q5REY6

Related

ENSPPYP00000039086.1, ENSPPYT00000053963.1

Conserved Domains (2) summary

smart00174
Location:8 → 181

RHO; Rho (Ras homology) subfamily of Ras-like small GTPases

cd01870
Location:5 → 179

RhoA_like; Ras homology family A (RhoA)-like includes RhoA, RhoB and RhoC