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chst6 carbohydrate sulfotransferase 6 [ Danio rerio (zebrafish) ]

Gene ID: 100170782, updated on 17-Aug-2024

Summary

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Official Symbol
chst6provided by ZNC
Official Full Name
carbohydrate sulfotransferase 6provided by ZNC
Primary source
ZFIN:ZDB-GENE-060810-74
See related
Ensembl:ENSDARG00000061357 AllianceGenome:ZFIN:ZDB-GENE-060810-74
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
im:7157221; zgc:194879
Summary
Predicted to enable N-acetylglucosamine 6-O-sulfotransferase activity. Predicted to be involved in N-acetylglucosamine metabolic process and sulfur compound metabolic process. Predicted to act upstream of or within carbohydrate metabolic process. Predicted to be located in Golgi membrane. Predicted to be integral component of membrane. Predicted to be active in trans-Golgi network. Human ortholog(s) of this gene implicated in macular corneal dystrophy. Orthologous to several human genes including CHST6 (carbohydrate sulfotransferase 6). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

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Location:
chromosome: 25
Exon count:
3
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 25 NC_007136.7 (34861672..34875320)
105 previous assembly GRCz10 (GCF_000002035.5) 25 NC_007136.6 (34356704..34366608)

Chromosome 25 - NC_007136.7Genomic Context describing neighboring genes Neighboring gene GABA(A) receptor-associated protein like 2 Neighboring gene transmembrane protein 231 Neighboring gene spire-type actin nucleation factor 2 Neighboring gene syntrophin, beta 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables N-acetylglucosamine 6-O-sulfotransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables sulfotransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in N-acetylglucosamine metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in sulfur compound metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in trans-Golgi network IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
carbohydrate sulfotransferase 6; uncharacterized protein LOC100170782
NP_001124093.1
XP_005163224.1
XP_017209529.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001130621.2 → NP_001124093.1  carbohydrate sulfotransferase 6

    See identical proteins and their annotated locations for NP_001124093.1

    Status: VALIDATED

    Source sequence(s)
    BX890570
    UniProtKB/TrEMBL
    A0A8M1NIT0, B3DIF5
    Related
    ENSDARP00000124000.1, ENSDART00000149782.2
    Conserved Domains (1) summary
    cl21551
    Location:170 → 359
    Sulfotransfer_1; Sulfotransferase domain

  2. NM_001430962.1 → NP_001417891.1  carbohydrate sulfotransferase 6

    Status: VALIDATED

    Source sequence(s)
    BX890570
    UniProtKB/TrEMBL
    A0A8M1NIT0, B3DIF5

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007136.7 Reference GRCz11 Primary Assembly

    Range
    34861672..34875320
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005163167.4 → XP_005163224.1  uncharacterized protein LOC100170782 isoform X1

    See identical proteins and their annotated locations for XP_005163224.1

    UniProtKB/TrEMBL
    A0A8M2BA60
    Conserved Domains (1) summary
    cl21551
    Location:207 → 396
    Sulfotransfer_1; Sulfotransferase domain

  2. XM_017354040.2 → XP_017209529.1  uncharacterized protein LOC100170782 isoform X2

    Conserved Domains (1) summary
    cl21551
    Location:170 → 359
    Sulfotransfer_1; Sulfotransferase domain
Nucleotide Protein
Heading Accession and Version

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