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greb1l GREB1 like retinoic acid receptor coactivator [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 100170499, updated on 4-Nov-2024

Summary

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Official Symbol
greb1lprovided by Xenbase
Official Full Name
GREB1 like retinoic acid receptor coactivatorprovided by Xenbase
Primary source
Xenbase:XB-GENE-5965356
See related
Ensembl:ENSXETG00000003149 AllianceGenome:Xenbase:XB-GENE-5965356
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Summary
Predicted to be involved in kidney development and morphogenesis of an epithelium. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness and renal agenesis. Orthologous to human GREB1L (GREB1 like retinoic acid receptor coactivator). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See greb1l in Genome Data Viewer
Location:
chromosome: 6
Exon count:
38
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 6 NC_030682.2 (108430259..108508153)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 6 NC_030682.1 (93364396..93441891)

Chromosome 6 - NC_030682.2Genomic Context describing neighboring genes Neighboring gene ubiquitin specific peptidase 14 Neighboring gene Rho-associated, coiled-coil containing protein kinase 1 Neighboring gene establishment of sister chromatid cohesion N-acetyltransferase 1 Neighboring gene abhydrolase domain containing 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Process Evidence Code Pubs
involved_in kidney development IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in morphogenesis of an epithelium IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
GREB1-like protein
Names
growth regulation by estrogen in breast cancer-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001130279.1 → NP_001123751.1  GREB1-like protein

    See identical proteins and their annotated locations for NP_001123751.1

    Status: PROVISIONAL

    Source sequence(s)
    BC167465
    UniProtKB/TrEMBL
    A0A6I8Q757, B3DLJ0
    Conserved Domains (1) summary
    pfam15782
    Location:1 → 1970
    GREB1; Gene regulated by oestrogen in breast cancer

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030682.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    108430259..108508153
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012964370.3 → XP_012819824.2  GREB1-like protein isoform X1

    UniProtKB/TrEMBL
    A0A6I8Q757, A0A8J0SUD4
    Conserved Domains (1) summary
    pfam15782
    Location:1 → 1973
    GREB1; Gene regulated by oestrogen in breast cancer

  2. XM_012964373.3 → XP_012819827.2  GREB1-like protein isoform X2

    UniProtKB/TrEMBL
    A0A6I8Q757, F6XP38
    Related
    ENSXETP00000006840.4, ENSXETT00000006840.4
    Conserved Domains (1) summary
    pfam15782
    Location:1 → 1970
    GREB1; Gene regulated by oestrogen in breast cancer

  3. XM_012964374.3 → XP_012819828.2  GREB1-like protein isoform X3

    UniProtKB/TrEMBL
    A0A6I8Q757, A0A8J0SQG6
    Related
    ENSXETP00000065385.2, ENSXETT00000092236.2
    Conserved Domains (1) summary
    pfam15782
    Location:1 → 1967
    GREB1; Gene regulated by oestrogen in breast cancer

  4. XM_031903256.1 → XP_031759116.1  GREB1-like protein isoform X1

    UniProtKB/TrEMBL
    A0A6I8Q757, A0A8J0SUD4
    Conserved Domains (1) summary
    pfam15782
    Location:1 → 1973
    GREB1; Gene regulated by oestrogen in breast cancer

  5. XM_018094566.2 → XP_017950055.2  GREB1-like protein isoform X1

    UniProtKB/TrEMBL
    A0A6I8Q757, A0A8J0SUD4
    Conserved Domains (1) summary
    pfam15782
    Location:1 → 1973
    GREB1; Gene regulated by oestrogen in breast cancer

  6. XM_012964371.3 → XP_012819825.2  GREB1-like protein isoform X1

    UniProtKB/TrEMBL
    A0A6I8Q757, A0A8J0SUD4
    Conserved Domains (1) summary
    pfam15782
    Location:1 → 1973
    GREB1; Gene regulated by oestrogen in breast cancer

  7. XM_012964372.3 → XP_012819826.2  GREB1-like protein isoform X1

    UniProtKB/TrEMBL
    A0A6I8Q757, A0A8J0SUD4
    Conserved Domains (1) summary
    pfam15782
    Location:1 → 1973
    GREB1; Gene regulated by oestrogen in breast cancer
Nucleotide Protein Strain
Heading Accession and Version

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