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CDH2 cadherin 2 [ Ovis aries (sheep) ]

Gene ID: 100170321, updated on 8-Mar-2024

Summary

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Gene symbol
CDH2
Gene description
cadherin 2
See related
EnsemblRapid:ENSOARG00020025259
Gene type
protein coding
RefSeq status
MODEL
Organism
Ovis aries
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
Orthologs
human mouse all
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Genomic context

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See CDH2 in Genome Data Viewer
Location:
chromosome: 23
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 23 NC_056076.1 (29012487..29254084)

Chromosome 23 - NC_056076.1Genomic Context describing neighboring genes Neighboring gene transfer RNA serine (anticodon GGA) Neighboring gene U1 spliceosomal RNA Neighboring gene NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2-like Neighboring gene large ribosomal subunit protein uL18-like Neighboring gene transfer RNA cysteine (anticodon ACA)

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_056076.1 Chromosome 23 Reference ARS-UI_Ramb_v3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Sequence diversity and rates of molecular evolution between sheep and cattle genes. Kijas JW, et al. Anim Genet, 2006 Apr. PMID 16573533
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cadherin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in adherens junction organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in blood vessel morphogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in brain development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell morphogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-cell junction assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in homophilic cell adhesion via plasma membrane adhesion molecules IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of axonogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of synaptic transmission, glutamatergic IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in synapse assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in adherens junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in apical part of cell IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of catenin complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in intercalated disc IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in lamellipodium IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in neuron projection IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in postsynaptic density IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in postsynaptic specialization membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in presynaptic active zone membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
cadherin-2
Names
cadherin 2, type 1, N-cadherin (neuronal)
neural-cadherin

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UI_Ramb_v3.0 Primary Assembly

Genomic

  1. NC_056076.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Range
    29012487..29254084
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_027960884.3 → XP_027816685.1  cadherin-2

    UniProtKB/TrEMBL
    W5PAD8
    Related
    ENSOARP00020032869.2, ENSOART00020039678.2
Nucleotide Protein Strain
Heading Accession and Version

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