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BHLHE40 basic helix-loop-helix family member e40 [ Ovis aries (sheep) ]

Gene ID: 100169939, updated on 8-Mar-2024

Summary

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Gene symbol
BHLHE40
Gene description
basic helix-loop-helix family member e40
See related
EnsemblRapid:ENSOARG00020012417
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Ovis aries
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
Also known as
BHLHB2
Orthologs
human mouse all
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Genomic context

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See BHLHE40 in Genome Data Viewer
Location:
chromosome: 19
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 19 NC_056072.1 (21380254..21384201, complement)

Chromosome 19 - NC_056072.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121817217 Neighboring gene uncharacterized LOC132658175 Neighboring gene uncharacterized LOC105603426 Neighboring gene inositol 1,4,5-trisphosphate receptor type 1 Neighboring gene uncharacterized LOC121817218 Neighboring gene sulfatase modifying factor 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_056072.1 Chromosome 19 Reference ARS-UI_Ramb_v3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Transcriptional feedback loops in the ovine circadian clock. Dardente H, et al. Comp Biochem Physiol A Mol Integr Physiol, 2009 Aug. PMID 19341811
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in anterior/posterior pattern specification IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in circadian regulation of gene expression IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of neurogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
class E basic helix-loop-helix protein 40
Names
Class B basic helix-loop-helix protein 2
basic helix-loop-helix domain containing class B2 protein
basic helix-loop-helix domain containing, class B, 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001129741.1 → NP_001123213.1  class E basic helix-loop-helix protein 40

    See identical proteins and their annotated locations for NP_001123213.1

    Status: PROVISIONAL

    Source sequence(s)
    EF494246
    UniProtKB/Swiss-Prot
    B3F209
    UniProtKB/TrEMBL
    A0A6M6I733, A0A836CSN8, W5PDA1
    Related
    ENSOARP00020015664.1, ENSOART00020018920.2
    Conserved Domains (2) summary
    smart00511
    Location:140 → 184
    ORANGE; Orange domain
    cd19749
    Location:40 → 129
    bHLH-O_DEC1; basic helix-loop-helix-orange (bHLH-O) domain found in differentially expressed in chondrocytes protein 1 (DEC1) and similar proteins

RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UI_Ramb_v3.0 Primary Assembly

Genomic

  1. NC_056072.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Range
    21380254..21384201 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
B3F209.1 GenPept UniProtKB/Swiss-Prot:B3F209

Gene LinkOut

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