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nln neurolysin (metallopeptidase M3 family) [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 100158603, updated on 4-Nov-2024

Summary

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Official Symbol
nlnprovided by Xenbase
Official Full Name
neurolysin (metallopeptidase M3 family)provided by Xenbase
Primary source
Xenbase:XB-GENE-960645
See related
Ensembl:ENSXETG00000000451 AllianceGenome:Xenbase:XB-GENE-960645
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Summary
Predicted to enable metal ion binding activity and metalloendopeptidase activity. Predicted to act upstream of or within proteolysis. Predicted to be located in cytoplasm. Orthologous to human NLN (neurolysin). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See nln in Genome Data Viewer
Location:
chromosome: 1
Exon count:
13
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 1 NC_030677.2 (187690946..187724961, complement)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 1 NC_030677.1 (174898565..174932568, complement)

Chromosome 1 - NC_030677.2Genomic Context describing neighboring genes Neighboring gene apurinic/apyrimidinic endodeoxyribonuclease 1 Neighboring gene uncharacterized LOC116407914 Neighboring gene uncharacterized LOC105947813 Neighboring gene small glutamine rich tetratricopeptide repeat co-chaperone beta Neighboring gene trafficking protein particle complex subunit 13

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables metalloendopeptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables metallopeptidase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within proteolysis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
neurolysin, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030677.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    187690946..187724961 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018090800.2 → XP_017946289.2  neurolysin, mitochondrial

    UniProtKB/TrEMBL
    A0A8J0SY07, B2GUK5
    Related
    ENSXETP00000000953.4, ENSXETT00000000953.4
    Conserved Domains (1) summary
    cd06455
    Location:58 → 695
    M3A_TOP; Peptidase M3 thimet oligopeptidase (TOP), also includes neurolysin
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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