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rhot1.L ras homolog family member T1 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 100158403, updated on 4-Nov-2024

Summary

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Official Symbol
rhot1.L
Official Full Name
ras homolog family member T1 L homeolog
Primary source
Xenbase:XB-GENE-866397
Locus tag
XELAEV_18044288mg
See related
EnsemblRapid:ENSXLAG00005018697 AllianceGenome:Xenbase:XB-GENE-866397
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
rhot1
Summary
Predicted to enable GTP binding activity; GTPase activity; and calcium ion binding activity. Predicted to act upstream of or within mitochondrion organization and small GTPase-mediated signal transduction. Predicted to be located in mitochondrial outer membrane. Orthologous to human RHOT1 (ras homolog family member T1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See rhot1.L in Genome Data Viewer
Location:
chromosome: 9_10L
Exon count:
21
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 9_10L NC_054387.1 (54778662..54798819, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 9_10L NC_030740.1 (44226747..44246909, complement)

Chromosome 9_10L - NC_054387.1Genomic Context describing neighboring genes Neighboring gene rhomboid-related protein 3 Neighboring gene uncharacterized LOC121398291 Neighboring gene uncharacterized LOC108701219 Neighboring gene E3 ubiquitin-protein ligase RNF135 Neighboring gene ArfGAP with dual PH domains 2 L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
  
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
  
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within mitochondrion organization IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within small GTPase-mediated signal transduction IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in mitochondrial outer membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ras homolog family member T1 L homeolog
Names
ras homolog gene family, member T1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001127846.1 → NP_001121318.1  ras homolog family member T1 L homeolog

    See identical proteins and their annotated locations for NP_001121318.1

    Status: PROVISIONAL

    Source sequence(s)
    BC124984
    UniProtKB/TrEMBL
    A0A974BYM3, Q08AW2
    Related
    ENSXLAP00005055606.1, ENSXLAT00005056811.1
    Conserved Domains (5) summary
    smart00174
    Location:7 → 169
    RHO; Rho (Ras homology) subfamily of Ras-like small GTPases
    cd01892
    Location:415 → 592
    Miro2; Mitochondrial Rho family 2 (Miro2), C-terminal
    cd01893
    Location:3 → 169
    Miro1; Mitochondrial Rho family 1 (Miro1), N-terminal
    pfam08355
    Location:341 → 409
    EF_assoc_1; EF hand associated
    pfam08356
    Location:221 → 301
    EF_assoc_2; EF hand associated

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054387.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    54778662..54798819 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041575444.1 → XP_041431378.1  ras homolog family member T1 L homeolog isoform X1

    UniProtKB/TrEMBL
    A0A1L8EV40, A0A974BYG4, A0A974BYM3
    Related
    ENSXLAP00005055643.1, ENSXLAT00005056848.1
    Conserved Domains (4) summary
    cd01892
    Location:415 → 581
    Miro2; Mitochondrial Rho family 2 (Miro2), C-terminal
    cd01893
    Location:3 → 169
    Miro1; Mitochondrial Rho family 1 (Miro1), N-terminal
    pfam08355
    Location:341 → 409
    EF_assoc_1; EF hand associated
    pfam08356
    Location:220 → 303
    EF_assoc_2; EF hand associated

  2. XM_018233947.2 → XP_018089436.1  ras homolog family member T1 L homeolog isoform X2

    UniProtKB/TrEMBL
    A0A8J0TQB4, A0A974BYM3
    Related
    ENSXLAP00005055654.1, ENSXLAT00005056859.1
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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