exd2.S exonuclease 3'-5' domain containing 2 S homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: exd2.S
Official Full Name: exonuclease 3'-5' domain containing 2 S homeolog
Primary source: Xenbase:XB-GENE-17342251
Locus tag: XELAEV_18041032mg
See related: EnsemblRapid:ENSXLAG00005021959 AllianceGenome:Xenbase:XB-GENE-17342251
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: exdl2; exd2-b
Summary: Predicted to enable 3'-5' exonuclease activity and nucleic acid binding activity. Predicted to act upstream of or within nucleobase-containing compound metabolic process. Predicted to be located in cytoplasm; membrane; and nucleus. Orthologous to human EXD2 (exonuclease 3'-5' domain containing 2). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 8S

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	8S	NC_054386.1 (2666866..2689795, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	8S	NC_030739.1 (2652128..2676912, complement)

Chromosome 8S - NC_054386.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables 3'-5' exonuclease activity	IEA Inferred from Electronic Annotation more info
enables exonuclease activity	IEA Inferred from Electronic Annotation more info
enables nuclease activity	IEA Inferred from Electronic Annotation more info
enables nucleic acid binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within nucleobase-containing compound metabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: exonuclease 3'-5' domain containing 2

Names: exonuclease 3'-5' domain containing 2 b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001127841.1 → NP_001121313.1 exonuclease 3'-5' domain containing 2

See identical proteins and their annotated locations for NP_001121313.1

Status: PROVISIONAL

Source sequence(s)

BC124971

UniProtKB/TrEMBL

Q08AX0, Q6PB18

Conserved Domains (1) summary

cd06141
Location:1 → 152

WRN_exo; DEDDy 3'-5' exonuclease domain of WRN and similar proteins