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tnnt3.L troponin T3, fast skeletal type L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 100158366, updated on 4-Nov-2024

Summary

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Official Symbol
tnnt3.L
Official Full Name
troponin T3, fast skeletal type L homeolog
Primary source
Xenbase:XB-GENE-864889
Locus tag
XELAEV_18022015mg
See related
EnsemblRapid:ENSXLAG00005020625 AllianceGenome:Xenbase:XB-GENE-864889
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Summary
Predicted to enable tropomyosin binding activity; troponin C binding activity; and troponin I binding activity. Predicted to act upstream of or within regulation of muscle contraction; sarcomere organization; and skeletal muscle contraction. Predicted to be part of troponin complex. Human ortholog(s) of this gene implicated in distal arthrogryposis type 2B and distal arthrogryposis type 2B2. Orthologous to human TNNT3 (troponin T3, fast skeletal type). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See tnnt3.L in Genome Data Viewer
Location:
chromosome: 4L
Exon count:
19
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 4L NC_054377.1 (16629421..16651591, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 4L NC_030730.1 (16113650..16135882, complement)

Chromosome 4L - NC_054377.1Genomic Context describing neighboring genes Neighboring gene insulin like growth factor 2 L homeolog Neighboring gene general transcription factor II-I repeat domain-containing protein 2 Neighboring gene flocculation protein FLO11-like Neighboring gene lymphocyte specific protein 1 L homeolog Neighboring gene troponin I2, fast skeletal type L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Molecular structure and developmental expression of three muscle-type troponin T genes in zebrafish. Hsiao CD, et al. Dev Dyn, 2003 Jun. PMID 12761854
  2. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables tropomyosin binding IEA
Inferred from Electronic Annotation
more info
  
enables troponin C binding IEA
Inferred from Electronic Annotation
more info
  
enables troponin I binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within regulation of muscle contraction IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within sarcomere organization IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within skeletal muscle contraction IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of troponin complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
troponin T3, fast skeletal type L homeolog
Names
fast troponin T

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001127811.1 → NP_001121283.1  troponin T3, fast skeletal type L homeolog

    See identical proteins and their annotated locations for NP_001121283.1

    Status: PROVISIONAL

    Source sequence(s)
    BC124917
    UniProtKB/TrEMBL
    Q08B15
    Related
    ENSXLAP00005060457.1, ENSXLAT00005061906.1
    Conserved Domains (2) summary
    pfam00992
    Location:51 → 187
    Troponin; Troponin
    pfam06936
    Location:74 → 175
    Selenoprotein_S; Selenoprotein S (SelS)

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054377.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    16629421..16651591 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041589088.1 → XP_041445022.1  troponin T3, fast skeletal type L homeolog isoform X4

    UniProtKB/TrEMBL
    A0A8J1MTC7, Q71N35
    Conserved Domains (1) summary
    PTZ00266
    Location:70 → 168
    PTZ00266; NIMA-related protein kinase; Provisional

  2. XM_018256358.2 → XP_018111847.1  troponin T3, fast skeletal type L homeolog isoform X5

    UniProtKB/TrEMBL
    A0A8J0USE1, Q71N35

  3. XM_041589087.1 → XP_041445021.1  troponin T3, fast skeletal type L homeolog isoform X3

    UniProtKB/TrEMBL
    A0A8J1MU80, Q71N35
    Conserved Domains (1) summary
    PTZ00266
    Location:71 → 169
    PTZ00266; NIMA-related protein kinase; Provisional

  4. XM_041589085.1 → XP_041445019.1  troponin T3, fast skeletal type L homeolog isoform X1

    UniProtKB/TrEMBL
    A0A8J1MT52
    Conserved Domains (2) summary
    PTZ00266
    Location:71 → 169
    PTZ00266; NIMA-related protein kinase; Provisional
    COG1196
    Location:79 → 263
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  5. XM_018256362.2 → XP_018111851.1  troponin T3, fast skeletal type L homeolog isoform X10

    UniProtKB/TrEMBL
    A0A8J0UYP5, Q71N35

  6. XM_041589092.1 → XP_041445026.1  troponin T3, fast skeletal type L homeolog isoform X12

    UniProtKB/TrEMBL
    A0A8J1MU85, Q71N35
    Related
    ENSXLAP00005060538.1, ENSXLAT00005061987.1
    Conserved Domains (1) summary
    PTZ00266
    Location:32 → 130
    PTZ00266; NIMA-related protein kinase; Provisional

  7. XM_041589089.1 → XP_041445023.1  troponin T3, fast skeletal type L homeolog isoform X7

    UniProtKB/TrEMBL
    A0A8J1MUJ6
    Conserved Domains (1) summary
    TIGR02168
    Location:47 → 226
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  8. XM_041589090.1 → XP_041445024.1  troponin T3, fast skeletal type L homeolog isoform X8

    UniProtKB/TrEMBL
    A0A8J1MT57, Q71N35
    Conserved Domains (1) summary
    PTZ00266
    Location:38 → 136
    PTZ00266; NIMA-related protein kinase; Provisional

  9. XM_018256361.2 → XP_018111850.1  troponin T3, fast skeletal type L homeolog isoform X6

    UniProtKB/TrEMBL
    A0A8J0UXG8

  10. XM_041589086.1 → XP_041445020.1  troponin T3, fast skeletal type L homeolog isoform X2

    UniProtKB/TrEMBL
    A0A8J1MVF9
    Related
    ENSXLAP00005060485.1, ENSXLAT00005061934.1
    Conserved Domains (1) summary
    TIGR02168
    Location:80 → 259
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  11. XM_041589093.1 → XP_041445027.1  troponin T3, fast skeletal type L homeolog isoform X13

    UniProtKB/TrEMBL
    A0A8J1MUK3
    Related
    ENSXLAP00005060512.1, ENSXLAT00005061962.1
    Conserved Domains (1) summary
    TIGR02168
    Location:36 → 215
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  12. XM_018256363.2 → XP_018111852.1  troponin T3, fast skeletal type L homeolog isoform X9

    UniProtKB/TrEMBL
    A0A8J0V2B7

  13. XM_041589091.1 → XP_041445025.1  troponin T3, fast skeletal type L homeolog isoform X11

    UniProtKB/TrEMBL
    A0A8J1MVG4
    Related
    ENSXLAP00005060469.1, ENSXLAT00005061918.1
    Conserved Domains (1) summary
    TIGR02168
    Location:41 → 220
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

  14. XM_041589094.1 → XP_041445028.1  troponin T3, fast skeletal type L homeolog isoform X13

    UniProtKB/TrEMBL
    A0A8J1MUK3
    Conserved Domains (1) summary
    TIGR02168
    Location:36 → 215
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
Nucleotide Protein Strain
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