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SORD sorbitol dehydrogenase [ Sus scrofa (pig) ]

Gene ID: 100158181, updated on 17-Aug-2024

Summary

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Official Symbol
SORDprovided by VGNC
Official Full Name
sorbitol dehydrogenaseprovided by VGNC
Primary source
VGNC:VGNC:93342
See related
Ensembl:ENSSSCG00000004679
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Also known as
SDH; XDH
Expression
Biased expression in liver (RPKM 597.1), mixtures (RPKM 253.9) and 1 other tissue See more
Orthologs
human mouse all
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Genomic context

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See SORD in Genome Data Viewer
Location:
chromosome: 1
Exon count:
9
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 1 NC_010443.5 (126659198..126701084, complement)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) 1 NC_010443.4 (141259120..141301021, complement)

Chromosome 1 - NC_010443.5Genomic Context describing neighboring genes Neighboring gene dual oxidase maturation factor 2 Neighboring gene dual oxidase 2 Neighboring gene telomere repeat binding bouquet formation protein 2 Neighboring gene uncharacterized protein C12orf31 homolog pseudogene Neighboring gene tripartite motif containing 69

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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Related articles in PubMed

  1. Comparative analysis of protein coding sequences from human, mouse and the domesticated pig. Jørgensen FG, et al. BMC Biol, 2005 Jan 28. PMID 15679890, Free PMC Article
  2. PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences. Uenishi H, et al. Nucleic Acids Res, 2007 Jan. PMID 17145712, Free PMC Article
  3. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article
  4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables L-iditol 2-dehydrogenase (NAD+) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in sorbitol catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
sorbitol dehydrogenase
Names
L-iditol 2-dehydrogenase
polyol dehydrogenase
xylitol dehydrogenase
NP_001231091.1
XP_020918345.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001244162.1 → NP_001231091.1  sorbitol dehydrogenase

    Status: VALIDATED

    Source sequence(s)
    AEMK02000004, AY610034
    UniProtKB/TrEMBL
    A0A480UJV9, A0A4X1VDW7, A0A8D0M8P2
    Conserved Domains (2) summary
    cd05285
    Location:10 → 349
    sorbitol_DH; Sorbitol dehydrogenase
    PLN02702
    Location:7 → 346
    PLN02702; L-idonate 5-dehydrogenase

RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010443.5 Reference Sscrofa11.1 Primary Assembly

    Range
    126659198..126701084 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021062686.1 → XP_020918345.1  sorbitol dehydrogenase isoform X1

    UniProtKB/TrEMBL
    A0A287AT21, A0A4X1VA34, A0A8D0M8P2, A0A8D0ZP72
    Related
    ENSSSCP00000047058.2, ENSSSCT00000055444.3
    Conserved Domains (1) summary
    cd05285
    Location:22 → 349
    sorbitol_DH; Sorbitol dehydrogenase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q29318.2 GenPept UniProtKB/Swiss-Prot:Q29318

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials