THBD thrombomodulin [Sus scrofa (pig)] - Gene

Summary

Gene symbol: THBD
Gene description: thrombomodulin
See related: Ensembl:ENSSSCG00000053422
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Sus scrofa
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 17

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
106	current	Sscrofa11.1 (GCF_000003025.6)	17	NC_010459.5 (30219870..30223499, complement)
105	previous assembly	Sscrofa10.2 (GCF_000003025.5)	17	NC_010459.4 (34274132..34277761, complement)

Chromosome 17 - NC_010459.5 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables calcium ion binding	IEA Inferred from Electronic Annotation more info	PubMed
enables transmembrane signaling receptor activity	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: thrombomodulin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001130732.1 → NP_001124204.1 thrombomodulin precursor

See identical proteins and their annotated locations for NP_001124204.1

Status: PROVISIONAL

Source sequence(s)

EF692640

UniProtKB/TrEMBL

A0A4X1V0Q9, A0A8W4FEQ7, B3STX8

Related

ENSSSCP00000076795.1, ENSSSCT00000098980.1

Conserved Domains (5) summary

pfam09064
Location:406 → 439

Tme5_EGF_like; Thrombomodulin like fifth domain, EGF-like

pfam12662
Location:306 → 327

cEGF; Complement Clr-like EGF-like

pfam14670
Location:244 → 279

FXa_inhibition; Coagulation Factor Xa inhibitory site

cl02432
Location:30 → 169

CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain

cl21504
Location:325 → 361

EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...