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PLCB2 phospholipase C beta 2 [ Sus scrofa (pig) ]

Gene ID: 100157641, updated on 17-Aug-2024

Summary

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Official Symbol
PLCB2provided by VGNC
Official Full Name
phospholipase C beta 2provided by VGNC
Primary source
VGNC:VGNC:91515
See related
Ensembl:ENSSSCG00000004779
Gene type
protein coding
RefSeq status
MODEL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Expression
Biased expression in spleen (RPKM 16.6), lung (RPKM 7.8) and 2 other tissues See more
Orthologs
human mouse all
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Genomic context

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See PLCB2 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
33
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 1 NC_010443.5 (131005408..131031864)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) 1 NC_010443.4 (146286447..146302118, complement)

Chromosome 1 - NC_010443.5Genomic Context describing neighboring genes Neighboring gene coiled-coil domain containing 9B Neighboring gene InaF motif containing 2 Neighboring gene ankyrin repeat domain 63 Neighboring gene p21 (RAC1) activated kinase 6 Neighboring gene BUB1 mitotic checkpoint serine/threonine kinase B

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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Related articles in PubMed

  1. PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences. Uenishi H, et al. Nucleic Acids Res, 2007 Jan. PMID 17145712, Free PMC Article
  2. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol phospholipase C activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in lipid catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010443.5 Reference Sscrofa11.1 Primary Assembly

    Range
    131005408..131031864
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021097762.1 → XP_020953421.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X1

    UniProtKB/TrEMBL
    A0A287BSY0, A0A5G2R283, A0A8D0Q7T0, A0A8D1HLH1
    Related
    ENSSSCP00000059295.1, ENSSSCT00000052016.3
    Conserved Domains (5) summary
    cd00275
    Location:688 → 809
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08624
    Location:311 → 656
    PI-PLCc_beta2; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta2
    cd13361
    Location:17 → 144
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    pfam08703
    Location:1005 → 1161
    PLC-beta_C; PLC-beta C terminal
    cd16209
    Location:149 → 299
    EFh_PI-PLCbeta2; EF-hand motif found in phosphoinositide phospholipase C beta 2 (PI-PLC-beta2)

  2. XM_021097773.1 → XP_020953432.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X2

    UniProtKB/TrEMBL
    A0A5G2R283, A0A8D0Q7T0
    Related
    ENSSSCP00000068307.1, ENSSSCT00000081376.2
    Conserved Domains (6) summary
    cd00275
    Location:688 → 809
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08624
    Location:311 → 656
    PI-PLCc_beta2; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta2
    cd13361
    Location:17 → 144
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    pfam08703
    Location:1004 → 1160
    PLC-beta_C; PLC-beta C terminal
    cd16209
    Location:149 → 299
    EFh_PI-PLCbeta2; EF-hand motif found in phosphoinositide phospholipase C beta 2 (PI-PLC-beta2)
    cl26511
    Location:858 → 1187
    Neuromodulin_N; Gap junction protein N-terminal region

  3. XM_021097783.1 → XP_020953442.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X3

    UniProtKB/TrEMBL
    A0A5G2R283, A0A8D0Q7T0
    Conserved Domains (5) summary
    cd00275
    Location:633 → 754
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08624
    Location:256 → 601
    PI-PLCc_beta2; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta2
    cd13361
    Location:1 → 89
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    pfam08703
    Location:950 → 1106
    PLC-beta_C; PLC-beta C terminal
    cd16209
    Location:94 → 244
    EFh_PI-PLCbeta2; EF-hand motif found in phosphoinositide phospholipase C beta 2 (PI-PLC-beta2)
Nucleotide Protein
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