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ASAH2 N-acylsphingosine amidohydrolase 2 [ Sus scrofa (pig) ]

Gene ID: 100157065, updated on 17-Aug-2024

Summary

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Official Symbol
ASAH2provided by VGNC
Official Full Name
N-acylsphingosine amidohydrolase 2provided by VGNC
Primary source
VGNC:VGNC:97888
See related
Ensembl:ENSSSCG00000010432
Gene type
protein coding
RefSeq status
MODEL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Also known as
ASAH2B
Expression
Low expression observed in reference dataset See more
Orthologs
human mouse all
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Genomic context

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See ASAH2 in Genome Data Viewer
Location:
chromosome: 14
Exon count:
24
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 14 NC_010456.5 (99018111..99141374, complement)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) 14 NC_010456.4 (107865243..107969067, complement)

Chromosome 14 - NC_010456.5Genomic Context describing neighboring genes Neighboring gene protein kinase cGMP-dependent 1 Neighboring gene cleavage stimulation factor subunit 2 tau variant Neighboring gene uncharacterized LOC110256620 Neighboring gene APOBEC1 complementation factor Neighboring gene sphingomyelin synthase 1 Neighboring gene rab GTPase-activating protein 1-like pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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Related articles in PubMed

  1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables N-acylsphingosine amidohydrolase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in ceramide catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in long-chain fatty acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in sphingosine biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
neutral ceramidase
Names
N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2B

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010456.5 Reference Sscrofa11.1 Primary Assembly

    Range
    99018111..99141374 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021072693.1 → XP_020928352.1  neutral ceramidase

    UniProtKB/TrEMBL
    A0A8D0MNE4, A0A8D1TSG6, F1SCZ9
    Conserved Domains (2) summary
    pfam04734
    Location:99 → 605
    Ceramidase_alk; Neutral/alkaline non-lysosomal ceramidase, N-terminal
    pfam17048
    Location:607 → 774
    Ceramidse_alk_C; Neutral/alkaline non-lysosomal ceramidase, C-terminal

  2. XM_021072694.1 → XP_020928353.1  neutral ceramidase

    UniProtKB/TrEMBL
    A0A8D0MNE4, A0A8D1TSG6, F1SCZ9
    Related
    ENSSSCP00000060774.1, ENSSSCT00000086528.2
    Conserved Domains (2) summary
    pfam04734
    Location:99 → 605
    Ceramidase_alk; Neutral/alkaline non-lysosomal ceramidase, N-terminal
    pfam17048
    Location:607 → 774
    Ceramidse_alk_C; Neutral/alkaline non-lysosomal ceramidase, C-terminal

  3. XM_005671250.3 → XP_005671307.1  neutral ceramidase

    UniProtKB/TrEMBL
    A0A8D0MNE4, A0A8D1TSG6, F1SCZ9
    Related
    ENSSSCP00000011121.3, ENSSSCT00000011417.4
    Conserved Domains (2) summary
    pfam04734
    Location:99 → 605
    Ceramidase_alk; Neutral/alkaline non-lysosomal ceramidase, N-terminal
    pfam17048
    Location:607 → 774
    Ceramidse_alk_C; Neutral/alkaline non-lysosomal ceramidase, C-terminal
Nucleotide Protein
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