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FBXW4 F-box and WD repeat domain containing 4 [ Sus scrofa (pig) ]

Gene ID: 100157051, updated on 17-Aug-2024

Summary

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Official Symbol
FBXW4provided by VGNC
Official Full Name
F-box and WD repeat domain containing 4provided by VGNC
Primary source
VGNC:VGNC:88055
See related
Ensembl:ENSSSCG00000010566
Gene type
protein coding
RefSeq status
MODEL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Expression
Ubiquitous expression in lung (RPKM 3.0), ovary (RPKM 2.9) and 8 other tissues See more
Orthologs
human mouse all
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Genomic context

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See FBXW4 in Genome Data Viewer
Location:
chromosome: 14
Exon count:
13
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 14 NC_010456.5 (112628988..112736631, complement)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) 14 NC_010456.4 (122381573..122481033, complement)

Chromosome 14 - NC_010456.5Genomic Context describing neighboring genes Neighboring gene beta-transducin repeat containing E3 ubiquitin protein ligase Neighboring gene DNA polymerase lambda Neighboring gene deleted in primary ciliary dyskinesia homolog (mouse) Neighboring gene uncharacterized LOC102162056 Neighboring gene fibroblast growth factor 8 Neighboring gene nucleophosmin/nucleoplasmin 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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Related articles in PubMed

  1. PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences. Uenishi H, et al. Nucleic Acids Res, 2007 Jan. PMID 17145712, Free PMC Article
  2. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of SCF ubiquitin ligase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
F-box/WD repeat-containing protein 4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010456.5 Reference Sscrofa11.1 Primary Assembly

    Range
    112628988..112736631 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021072714.1 → XP_020928373.1  F-box/WD repeat-containing protein 4 isoform X1

    UniProtKB/TrEMBL
    A0A480R9K0, A0A4X1U0Z8
    Conserved Domains (3) summary
    sd00039
    Location:427 → 468
    7WD40; WD40 repeat [structural motif]
    pfam12937
    Location:191 → 223
    F-box-like
    cl25539
    Location:304 → 578
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  2. XM_001924973.5 → XP_001925008.4  F-box/WD repeat-containing protein 4 isoform X3

    UniProtKB/TrEMBL
    A0A480R9K0, A0A480ZDE8, A0A4X1U0Z8
    Related
    ENSSSCP00000011256.4, ENSSSCT00000011558.5
    Conserved Domains (3) summary
    sd00039
    Location:358 → 394
    7WD40; WD40 repeat [structural motif]
    pfam12937
    Location:191 → 223
    F-box-like
    cl25539
    Location:304 → 551
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  3. XM_021072715.1 → XP_020928374.1  F-box/WD repeat-containing protein 4 isoform X2

    UniProtKB/TrEMBL
    A0A4X1TY29
    Conserved Domains (3) summary
    sd00039
    Location:318 → 350
    7WD40; WD40 repeat [structural motif]
    pfam12937
    Location:191 → 223
    F-box-like
    cl25539
    Location:304 → 556
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  4. XM_021072716.1 → XP_020928375.1  F-box/WD repeat-containing protein 4 isoform X4

    UniProtKB/TrEMBL
    A0A4X1TY29
    Conserved Domains (3) summary
    sd00039
    Location:318 → 350
    7WD40; WD40 repeat [structural motif]
    pfam12937
    Location:191 → 223
    F-box-like
    cl25539
    Location:304 → 529
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  5. XM_021072719.1 → XP_020928378.1  F-box/WD repeat-containing protein 4 isoform X6

    Conserved Domains (3) summary
    sd00039
    Location:384 → 416
    7WD40; WD40 repeat [structural motif]
    pfam12937
    Location:257 → 289
    F-box-like
    cl25539
    Location:372 → 499
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  6. XM_021072718.1 → XP_020928377.1  F-box/WD repeat-containing protein 4 isoform X5

    Conserved Domains (3) summary
    sd00039
    Location:384 → 416
    7WD40; WD40 repeat [structural motif]
    pfam12937
    Location:257 → 289
    F-box-like
    cl25539
    Location:372 → 499
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RNA

  1. XR_002338434.1 RNA Sequence

  2. XR_002338437.1 RNA Sequence

  3. XR_002338438.1 RNA Sequence

  4. XR_002338435.1 RNA Sequence

  5. XR_002338440.1 RNA Sequence

  6. XR_002338436.1 RNA Sequence

  7. XR_002338439.1 RNA Sequence

    Related
    ENSSSCT00000053883.3

  8. XR_002338441.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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