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HPGD 15-hydroxyprostaglandin dehydrogenase [ Sus scrofa (pig) ]

Gene ID: 100156186, updated on 17-Aug-2024

Summary

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Official Symbol
HPGDprovided by VGNC
Official Full Name
15-hydroxyprostaglandin dehydrogenaseprovided by VGNC
Primary source
VGNC:VGNC:88961
See related
Ensembl:ENSSSCG00000009699
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Expression
Broad expression in spleen (RPKM 34.5), liver (RPKM 22.5) and 5 other tissues See more
Orthologs
human mouse all
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Genomic context

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See HPGD in Genome Data Viewer
Location:
chromosome: 14
Exon count:
12
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 14 NC_010456.5 (15718261..15773534)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) 14 NC_010456.4 (16909010..16921261)

Chromosome 14 - NC_010456.5Genomic Context describing neighboring genes Neighboring gene glycine receptor alpha 3 Neighboring gene uncharacterized LOC110256873 Neighboring gene 40S ribosomal protein S26-like Neighboring gene E3 ubiquitin-protein ligase RNF168 pseudogene Neighboring gene centrosomal protein 44 Neighboring gene F-box protein 8 Neighboring gene uncharacterized LOC102163133

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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Related articles in PubMed

  1. Comparative analysis of protein coding sequences from human, mouse and the domesticated pig. Jørgensen FG, et al. BMC Biol, 2005 Jan 28. PMID 15679890, Free PMC Article
  2. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
15-hydroxyprostaglandin dehydrogenase [NAD(+)]
Names
hydroxyprostaglandin dehydrogenase 15-(NAD)
NP_001177177.1
XP_020927633.1
XP_020927634.1
XP_020927635.1
XP_020927636.1
XP_020927637.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001190248.1 → NP_001177177.1  15-hydroxyprostaglandin dehydrogenase [NAD(+)]

    See identical proteins and their annotated locations for NP_001177177.1

    Status: PROVISIONAL

    Source sequence(s)
    AB529533
    UniProtKB/TrEMBL
    A0A4X1V850, A0A8D1WXZ3, D0G6X9, F6PT21
    Related
    ENSSSCP00000010358.3, ENSSSCT00000010634.4
    Conserved Domains (2) summary
    cd05323
    Location:6 → 254
    ADH_SDR_c_like; insect type alcohol dehydrogenase (ADH)-like, classical (c) SDRs
    pfam00106
    Location:6 → 199
    adh_short; short chain dehydrogenase

RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010456.5 Reference Sscrofa11.1 Primary Assembly

    Range
    15718261..15773534
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021071975.1 → XP_020927634.1  15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform X2

    UniProtKB/TrEMBL
    A0A4X1V860, A0A5G2R1D3
    Conserved Domains (1) summary
    cl25409
    Location:6 → 141
    SDR; Short-chain dehydrogenases/reductases (SDR)

  2. XM_021071977.1 → XP_020927636.1  15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform X2

    UniProtKB/TrEMBL
    A0A4X1V860, A0A5G2R1D3
    Conserved Domains (1) summary
    cl25409
    Location:6 → 141
    SDR; Short-chain dehydrogenases/reductases (SDR)

  3. XM_021071976.1 → XP_020927635.1  15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform X2

    UniProtKB/TrEMBL
    A0A4X1V860, A0A5G2R1D3
    Conserved Domains (1) summary
    cl25409
    Location:6 → 141
    SDR; Short-chain dehydrogenases/reductases (SDR)

  4. XM_021071978.1 → XP_020927637.1  15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform X3

    UniProtKB/TrEMBL
    A0A4X1V860, A0A5G2R1D3
    Related
    ENSSSCP00000070923.1, ENSSSCT00000086201.2
    Conserved Domains (1) summary
    cl25409
    Location:6 → 141
    SDR; Short-chain dehydrogenases/reductases (SDR)

  5. XM_021071974.1 → XP_020927633.1  15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform X1

    Conserved Domains (1) summary
    cl25409
    Location:21 → 169
    SDR; Short-chain dehydrogenases/reductases (SDR)

RNA

  1. XR_002338278.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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