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PTGES3 prostaglandin E synthase 3 [ Sus scrofa (pig) ]

Gene ID: 100155956, updated on 17-Aug-2024

Summary

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Official Symbol
PTGES3provided by VGNC
Official Full Name
prostaglandin E synthase 3provided by VGNC
Primary source
VGNC:VGNC:91952
See related
Ensembl:ENSSSCG00000000406
Gene type
protein coding
RefSeq status
MODEL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Expression
Ubiquitous expression in ovary (RPKM 45.7), kidney (RPKM 31.7) and 8 other tissues See more
Orthologs
human mouse all
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Genomic context

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See PTGES3 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
8
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 5 NC_010447.5 (22000335..22022830, complement)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) 5 NC_010447.4 (23674707..23696337, complement)

Chromosome 5 - NC_010447.5Genomic Context describing neighboring genes Neighboring gene RNA binding motif single stranded interacting protein 2 Neighboring gene bromodomain adjacent to zinc finger domain 2A Neighboring gene ATP synthase F1 subunit beta Neighboring gene nascent polypeptide associated complex subunit alpha Neighboring gene DNA primase subunit 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables Hsp90 protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables prostaglandin-E synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein-folding chaperone binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in chaperone-mediated protein complex assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in prostaglandin biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein folding IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in telomerase holoenzyme complex assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in telomere maintenance via telomerase IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
prostaglandin E synthase 3
Names
unactive progesterone receptor, 23 kD

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010447.5 Reference Sscrofa11.1 Primary Assembly

    Range
    22000335..22022830 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005663892.3 → XP_005663949.1  prostaglandin E synthase 3 isoform X2

    See identical proteins and their annotated locations for XP_005663949.1

    UniProtKB/TrEMBL
    A0A5G2QTM2, A0A8D1GTB2, A0A8D1YC89
    Related
    ENSSSCP00000068188.1, ENSSSCT00000068317.2
    Conserved Domains (1) summary
    cd00237
    Location:3 → 109
    p23; p23 binds heat shock protein (Hsp)90 and participates in the folding of a number of Hsp90 clients, including the progesterone receptor. p23 also has a passive chaperoning activity and in addition may participate in prostaglandin synthesis.

  2. XM_001929413.6 → XP_001929448.3  prostaglandin E synthase 3 isoform X1

    See identical proteins and their annotated locations for XP_001929448.3

    UniProtKB/TrEMBL
    A0A8D1SXV8, A0A8D1UEM7, F1SL99
    Related
    ENSSSCP00000000433.3, ENSSSCT00000000439.6
    Conserved Domains (1) summary
    cd00237
    Location:3 → 109
    p23; p23 binds heat shock protein (Hsp)90 and participates in the folding of a number of Hsp90 clients, including the progesterone receptor. p23 also has a passive chaperoning activity and in addition may participate in prostaglandin synthesis.

RNA

  1. XR_002344304.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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