U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

HSD17B8 hydroxysteroid 17-beta dehydrogenase 8 [ Sus scrofa (pig) ]

Gene ID: 100154372, updated on 17-Aug-2024

Summary

Go to the top of the page Help
Official Symbol
HSD17B8provided by VGNC
Official Full Name
hydroxysteroid 17-beta dehydrogenase 8provided by VGNC
Primary source
VGNC:VGNC:88989
See related
Ensembl:ENSSSCG00000001476
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Also known as
KE6; HKE6; Ke-6; FABGL
Expression
Ubiquitous expression in kidney (RPKM 49.2), heart (RPKM 48.3) and 8 other tissues See more
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See HSD17B8 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
9
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 7 NC_010449.5 (25247577..25249786)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) 7 NC_010449.4 (29753837..29756042, complement)

Chromosome 7 - NC_010449.5Genomic Context describing neighboring genes Neighboring gene retinoid X receptor beta Neighboring gene solute carrier family 39 member 7 Neighboring gene microRNA mir-219a Neighboring gene ring finger protein 1

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables estradiol 17-beta-dehydrogenase [NAD(P)+] activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in estrogen biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
(3R)-3-hydroxyacyl-CoA dehydrogenase; estradiol 17-beta-dehydrogenase 8
Names
17-beta-HSD 8
17-beta-hydroxysteroid dehydrogenase 8
3-ketoacyl-[acyl-carrier-protein] reductase alpha subunit
3-oxoacyl-[acyl-carrier-protein] reductase
Estradiol 17-beta-dehydrogenase 8
FabG-like protein FABGL
KAR alpha subunit
Protein Ke6
Testosterone 17-beta-dehydrogenase 8
NP_001124202.1
XP_005665911.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001130730.1 → NP_001124202.1  (3R)-3-hydroxyacyl-CoA dehydrogenase

    See identical proteins and their annotated locations for NP_001124202.1

    Status: PROVISIONAL

    Source sequence(s)
    BX640585
    UniProtKB/Swiss-Prot
    Q9XT00
    UniProtKB/TrEMBL
    A0A8D0TRR3, A5D9P1
    Related
    ENSSSCP00000001605.2, ENSSSCT00000001647.5
    Conserved Domains (2) summary
    PRK05653
    Location:12 → 259
    fabG; 3-ketoacyl-(acyl-carrier-protein) reductase; Validated
    cl21454
    Location:11 → 258
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010449.5 Reference Sscrofa11.1 Primary Assembly

    Range
    25247577..25249786
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005665854.3 → XP_005665911.1  estradiol 17-beta-dehydrogenase 8 isoform X1

    UniProtKB/TrEMBL
    A0A8D1AAP1
    Related
    ENSSSCP00000028689.2, ENSSSCT00000034292.4
    Conserved Domains (2) summary
    pfam00106
    Location:12 → 213
    adh_short; short chain dehydrogenase
    cl21454
    Location:11 → 219
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9XT00.2 GenPept UniProtKB/Swiss-Prot:Q9XT00

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.