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PLA2G12B phospholipase A2 group XIIB [ Sus scrofa (pig) ]

Gene ID: 100152597, updated on 18-Sep-2024

Summary

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Official Symbol
PLA2G12Bprovided by VGNC
Official Full Name
phospholipase A2 group XIIBprovided by VGNC
Primary source
VGNC:VGNC:91489
See related
Ensembl:ENSSSCG00000010291
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Expression
Biased expression in liver (RPKM 91.3) and mixtures (RPKM 33.7) See more
Orthologs
human mouse all
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Genomic context

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See PLA2G12B in Genome Data Viewer
Location:
chromosome: 14
Exon count:
4
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 14 NC_010456.5 (75754525..75778933, complement)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) 14 NC_010456.4 (81819851..81844252, complement)

Chromosome 14 - NC_010456.5Genomic Context describing neighboring genes Neighboring gene mitochondrial calcium uniporter Neighboring gene oncoprotein induced transcript 3 Neighboring gene transfer RNA leucine (anticodon UAA) Neighboring gene prolyl 4-hydroxylase subunit alpha 1 Neighboring gene nudix hydrolase 13 Neighboring gene ecdysoneless cell cycle regulator

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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Related articles in PubMed

  1. Porcine transcriptome analysis based on 97 non-normalized cDNA libraries and assembly of 1,021,891 expressed sequence tags. Gorodkin J, et al. Genome Biol, 2007. PMID 17407547, Free PMC Article
  2. PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences. Uenishi H, et al. Nucleic Acids Res, 2007 Jan. PMID 17145712, Free PMC Article
  3. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article
  4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phospholipase A2 activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in arachidonate secretion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cholesterol homeostasis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in lipid catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phospholipid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in triglyceride homeostasis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
group XIIB secretory phospholipase A2-like protein
NP_001230267.1
XP_005671110.1
XP_005671111.1
XP_005671112.1
XP_020927539.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001243338.1 → NP_001230267.1  group XIIB secretory phospholipase A2-like protein precursor

    Status: VALIDATED

    Source sequence(s)
    AK345294, AK346162, EW113750
    UniProtKB/TrEMBL
    A0A4X1T5X7, F1SU77
    Related
    ENSSSCP00000010971.2, ENSSSCT00000011263.5
    Conserved Domains (1) summary
    pfam06951
    Location:18 → 194
    PLA2G12; Group XII secretory phospholipase A2 precursor (PLA2G12)

RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010456.5 Reference Sscrofa11.1 Primary Assembly

    Range
    75754525..75778933 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021071880.1 → XP_020927539.1  group XIIB secretory phospholipase A2-like protein isoform X4

    Conserved Domains (1) summary
    pfam06951
    Location:11 → 105
    PLA2G12; Group XII secretory phospholipase A2 precursor (PLA2G12)

  2. XM_005671055.3 → XP_005671112.1  group XIIB secretory phospholipase A2-like protein isoform X3

    Conserved Domains (1) summary
    pfam06951
    Location:18 → 190
    PLA2G12; Group XII secretory phospholipase A2 precursor (PLA2G12)

  3. XM_005671054.3 → XP_005671111.1  group XIIB secretory phospholipase A2-like protein isoform X2

    Conserved Domains (1) summary
    pfam06951
    Location:18 → 191
    PLA2G12; Group XII secretory phospholipase A2 precursor (PLA2G12)

  4. XM_005671053.3 → XP_005671110.1  group XIIB secretory phospholipase A2-like protein isoform X1

    UniProtKB/TrEMBL
    A0A8D0IF95
    Conserved Domains (1) summary
    pfam06951
    Location:18 → 195
    PLA2G12; Group XII secretory phospholipase A2 precursor (PLA2G12)
Nucleotide Protein
Heading Accession and Version

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