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polg2 polymerase (DNA directed), gamma 2, accessory subunit [ Danio rerio (zebrafish) ]

Gene ID: 100150674, updated on 2-Nov-2024

Summary

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Official Symbol
polg2provided by ZNC
Official Full Name
polymerase (DNA directed), gamma 2, accessory subunitprovided by ZNC
Primary source
ZFIN:ZDB-GENE-060810-116
See related
Ensembl:ENSDARG00000074933 AllianceGenome:ZFIN:ZDB-GENE-060810-116
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
im:7158733; si:ch211-157f15.3
Summary
Predicted to be involved in mitochondrial DNA replication. Predicted to be active in mitochondrion. Is expressed in eye and retina. Human ortholog(s) of this gene implicated in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 4; mitochondrial DNA depletion syndrome 16; and mitochondrial DNA depletion syndrome 16B. Orthologous to human POLG2 (DNA polymerase gamma 2, accessory subunit). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See polg2 in Genome Data Viewer
Location:
chromosome: 6
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (23010381..23024436)
105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (17912434..17928114)

Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene nucleolar protein 11 Neighboring gene transfer RNA arginine (anticodon CCG) Neighboring gene signal recognition particle 68 Neighboring gene envoplakin a

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
involved_in mitochondrial DNA replication IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
DNA polymerase subunit gamma-2, mitochondrial; DNA polymerase subunit gamma-2
XP_001922359.2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007117.7 Reference GRCz11 Primary Assembly

    Range
    23010381..23024436
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001922324.8 → XP_001922359.2  DNA polymerase subunit gamma-2

    UniProtKB/TrEMBL
    A0A8M1QV74, E7F4P9
    Related
    ENSDARP00000099588.2, ENSDART00000113116.5
    Conserved Domains (3) summary
    PRK04173
    Location:40 → 436
    PRK04173; glycyl-tRNA synthetase; Provisional
    cl00266
    Location:320 → 438
    HGTP_anticodon; HGTP anticodon binding domain, as found at the C-terminus of histidyl, glycyl, threonyl and prolyl tRNA synthetases, which are classified as a group of class II aminoacyl-tRNA synthetases (aaRS). In aaRSs, the anticodon binding domain is responsible for ...
    cl00268
    Location:40 → 309
    class_II_aaRS-like_core; Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA. PheRS is an exception in that it attaches ...
Nucleotide Protein Strain
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