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NCAN neurocan [ Equus caballus (horse) ]

Gene ID: 100147158, updated on 8-Mar-2024

Summary

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Official Symbol
NCANprovided by VGNC
Official Full Name
neurocanprovided by VGNC
Primary source
VGNC:VGNC:58196
See related
Ensembl:ENSECAG00000016115
Gene type
protein coding
RefSeq status
MODEL
Organism
Equus caballus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Orthologs
human mouse all
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Genomic context

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See NCAN in Genome Data Viewer
Location:
chromosome: 21
Exon count:
17
Annotation release Status Assembly Chr Location
103 current EquCab3.0 (GCF_002863925.1) 21 NC_009164.3 (4326917..4353655)
102 previous assembly EquCab2.0 (GCF_000002305.2) 21 NC_009164.2 (3697464..3723160)

Chromosome 21 - NC_009164.3Genomic Context describing neighboring genes Neighboring gene myocyte-specific enhancer factor 2B Neighboring gene BLOC-1 related complex subunit 8 Neighboring gene regulatory factor X associated ankyrin containing protein Neighboring gene nuclear receptor 2C2 associated protein Neighboring gene hyaluronan and proteoglycan link protein 4 Neighboring gene transmembrane 6 superfamily member 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables hyaluronic acid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
neurocan core protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Equus caballus Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference EquCab3.0 Primary Assembly

Genomic

  1. NC_009164.3 Reference EquCab3.0 Primary Assembly

    Range
    4326917..4353655
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_023625539.1 → XP_023481307.1  neurocan core protein

    UniProtKB/TrEMBL
    A0A9L0TNK0, F6V964
    Related
    ENSECAP00000013738.3, ENSECAT00000016969.4
    Conserved Domains (8) summary
    cd00033
    Location:1259 → 1315
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    cd00054
    Location:1090 → 1126
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd03517
    Location:163 → 257
    Link_domain_CSPGs_modules_1_3; this extracellular link domain is found in the first and third link modules of the chondroitin sulfate proteoglycan core protein (CSPG) aggrecan. In addition, it is found in the first link module of three other CSPGs: versican, neurocan, and brevican. ...
    cd03520
    Location:264 → 359
    Link_domain_CSPGs_modules_2_4; this link domain is found in the second and fourth link modules of the chondroitin sulfate proteoglycan core protein (CSPG) aggrecan and, in the second link module of three other CSPGs: versican, neurocan, and brevican. The link domain is a hyaluronan ...
    pfam00008
    Location:1056 → 1086
    EGF; EGF-like domain
    cl02432
    Location:1132 → 1255
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
    cl11960
    Location:54 → 164
    Ig; Immunoglobulin domain
    cl28033
    Location:355 → 775
    Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region

  2. XM_023625540.1 → XP_023481308.1  neurocan core protein

    UniProtKB/TrEMBL
    A0A9L0TNK0, F6V964
    Related
    ENSECAP00000089835.1, ENSECAT00000143567.1
    Conserved Domains (8) summary
    cd00033
    Location:1259 → 1315
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    cd00054
    Location:1090 → 1126
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd03517
    Location:163 → 257
    Link_domain_CSPGs_modules_1_3; this extracellular link domain is found in the first and third link modules of the chondroitin sulfate proteoglycan core protein (CSPG) aggrecan. In addition, it is found in the first link module of three other CSPGs: versican, neurocan, and brevican. ...
    cd03520
    Location:264 → 359
    Link_domain_CSPGs_modules_2_4; this link domain is found in the second and fourth link modules of the chondroitin sulfate proteoglycan core protein (CSPG) aggrecan and, in the second link module of three other CSPGs: versican, neurocan, and brevican. The link domain is a hyaluronan ...
    pfam00008
    Location:1056 → 1086
    EGF; EGF-like domain
    cl02432
    Location:1132 → 1255
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
    cl11960
    Location:54 → 164
    Ig; Immunoglobulin domain
    cl28033
    Location:355 → 775
    Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region

  3. XM_023625541.1 → XP_023481309.1  neurocan core protein

    UniProtKB/TrEMBL
    A0A9L0TNK0, F6V964
    Conserved Domains (8) summary
    cd00033
    Location:1259 → 1315
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    cd00054
    Location:1090 → 1126
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd03517
    Location:163 → 257
    Link_domain_CSPGs_modules_1_3; this extracellular link domain is found in the first and third link modules of the chondroitin sulfate proteoglycan core protein (CSPG) aggrecan. In addition, it is found in the first link module of three other CSPGs: versican, neurocan, and brevican. ...
    cd03520
    Location:264 → 359
    Link_domain_CSPGs_modules_2_4; this link domain is found in the second and fourth link modules of the chondroitin sulfate proteoglycan core protein (CSPG) aggrecan and, in the second link module of three other CSPGs: versican, neurocan, and brevican. The link domain is a hyaluronan ...
    pfam00008
    Location:1056 → 1086
    EGF; EGF-like domain
    cl02432
    Location:1132 → 1255
    CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
    cl11960
    Location:54 → 164
    Ig; Immunoglobulin domain
    cl28033
    Location:355 → 775
    Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region
Nucleotide Protein
Heading Accession and Version

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