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BST2 bone marrow stromal cell antigen 2 [ Equus caballus (horse) ]

Gene ID: 100146856, updated on 17-Aug-2024

Summary

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Official Symbol
BST2provided by VGNC
Official Full Name
bone marrow stromal cell antigen 2provided by VGNC
Primary source
VGNC:VGNC:96656
See related
Ensembl:ENSECAG00000003563
Gene type
protein coding
RefSeq status
MODEL
Organism
Equus caballus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Orthologs
human mouse all
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Genomic context

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See BST2 in Genome Data Viewer
Location:
chromosome: 21
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_08 current EquCab3.0 (GCF_002863925.1) 21 NC_009164.3 (2984341..2986696, complement)

Chromosome 21 - NC_009164.3Genomic Context describing neighboring genes Neighboring gene plasmalemma vesicle associated protein Neighboring gene coiled-coil domain containing 194 Neighboring gene multivesicular body subunit 12A Neighboring gene transmembrane protein 221

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_009164.3 Chromosome 21 Reference EquCab3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Equine tetherin blocks retrovirus release and its activity is antagonized by equine infectious anemia virus envelope protein. Yin X, et al. J Virol, 2014 Jan. PMID 24227834, Free PMC Article
  2. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Equine tetherin is localized on the cell surface and strongly blocks retrovirus release.
    Title: Equine tetherin blocks retrovirus release and its activity is antagonized by equine infectious anemia virus envelope protein.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metalloendopeptidase inhibitor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in defense response to virus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in innate immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cell surface IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
bone marrow stromal antigen 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference EquCab3.0 Primary Assembly

Genomic

  1. NC_009164.3 Reference EquCab3.0 Primary Assembly

    Range
    2984341..2986696 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005604172.3 → XP_005604229.3  bone marrow stromal antigen 2

    UniProtKB/TrEMBL
    A0A9L0TJT0, W8E3X2
    Related
    ENSECAP00000088529.1, ENSECAT00000117012.1
    Conserved Domains (1) summary
    pfam16716
    Location:75 → 162
    BST2; Bone marrow stromal antigen 2
Nucleotide Protein
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