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MAST3 microtubule associated serine/threonine kinase 3 [ Equus caballus (horse) ]

Gene ID: 100146664, updated on 17-Aug-2024

Summary

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Official Symbol
MAST3provided by VGNC
Official Full Name
microtubule associated serine/threonine kinase 3provided by VGNC
Primary source
VGNC:VGNC:58188
See related
Ensembl:ENSECAG00000008102
Gene type
protein coding
RefSeq status
MODEL
Organism
Equus caballus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Orthologs
human mouse all
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Genomic context

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See MAST3 in Genome Data Viewer
Location:
chromosome: 21
Exon count:
33
Annotation release Status Assembly Chr Location
RS_2024_08 current EquCab3.0 (GCF_002863925.1) 21 NC_009164.3 (3455624..3491188)

Chromosome 21 - NC_009164.3Genomic Context describing neighboring genes Neighboring gene arrestin domain containing 2 Neighboring gene uncharacterized LOC102149296 Neighboring gene interleukin 12 receptor subunit beta 1 Neighboring gene uncharacterized LOC111769670 Neighboring gene phosphoinositide-3-kinase regulatory subunit 2 Neighboring gene IFI30 lysosomal thiol reductase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_009164.3 Chromosome 21 Reference EquCab3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in peptidyl-serine phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
microtubule-associated serine/threonine-protein kinase 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_002863925.1-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference EquCab3.0 Primary Assembly

Genomic

  1. NC_009164.3 Reference EquCab3.0 Primary Assembly

    Range
    3455624..3491188
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_023625472.1 → XP_023481240.1  microtubule-associated serine/threonine-protein kinase 3 isoform X3

    UniProtKB/TrEMBL
    A0A9L0RD67
    Conserved Domains (3) summary
    smart00228
    Location:977 → 1058
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd05609
    Location:398 → 677
    STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
    pfam08926
    Location:88 → 362
    DUF1908; Domain of unknown function (DUF1908)

  2. XM_023625478.1 → XP_023481246.1  microtubule-associated serine/threonine-protein kinase 3 isoform X9

    UniProtKB/TrEMBL
    A0A9L0S0J4, F6PV89
    Related
    ENSECAP00000022905.4, ENSECAT00000028876.4
    Conserved Domains (3) summary
    cd00992
    Location:947 → 1028
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd05609
    Location:368 → 647
    STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
    pfam08926
    Location:58 → 332
    DUF1908; Domain of unknown function (DUF1908)

  3. XM_023625479.1 → XP_023481247.1  microtubule-associated serine/threonine-protein kinase 3 isoform X10

    UniProtKB/TrEMBL
    A0A9L0S0J4
    Conserved Domains (3) summary
    cd00992
    Location:946 → 1027
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd05609
    Location:367 → 646
    STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
    pfam08926
    Location:57 → 331
    DUF1908; Domain of unknown function (DUF1908)

  4. XM_023625480.1 → XP_023481248.1  microtubule-associated serine/threonine-protein kinase 3 isoform X11

    UniProtKB/TrEMBL
    A0A3Q2H751, A0A9L0S0J4
    Related
    ENSECAP00000029659.2, ENSECAT00000048482.2
    Conserved Domains (3) summary
    smart00228
    Location:937 → 1018
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd05609
    Location:358 → 637
    STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
    pfam08926
    Location:48 → 322
    DUF1908; Domain of unknown function (DUF1908)

  5. XM_023625481.1 → XP_023481249.1  microtubule-associated serine/threonine-protein kinase 3 isoform X11

    UniProtKB/TrEMBL
    A0A3Q2H751, A0A9L0S0J4
    Conserved Domains (3) summary
    smart00228
    Location:937 → 1018
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd05609
    Location:358 → 637
    STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
    pfam08926
    Location:48 → 322
    DUF1908; Domain of unknown function (DUF1908)

  6. XM_023625473.1 → XP_023481241.1  microtubule-associated serine/threonine-protein kinase 3 isoform X4

    UniProtKB/TrEMBL
    A0A9L0RD67
    Related
    ENSECAP00000063045.1, ENSECAT00000143253.1
    Conserved Domains (3) summary
    smart00228
    Location:969 → 1050
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd05609
    Location:390 → 669
    STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
    pfam08926
    Location:80 → 354
    DUF1908; Domain of unknown function (DUF1908)

  7. XM_023625470.1 → XP_023481238.1  microtubule-associated serine/threonine-protein kinase 3 isoform X1

    UniProtKB/TrEMBL
    A0A9L0RD67
    Conserved Domains (3) summary
    cd00992
    Location:1021 → 1102
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd05609
    Location:442 → 721
    STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
    pfam08926
    Location:132 → 406
    DUF1908; Domain of unknown function (DUF1908)

  8. XM_023625471.1 → XP_023481239.1  microtubule-associated serine/threonine-protein kinase 3 isoform X2

    UniProtKB/TrEMBL
    A0A9L0RD67
    Conserved Domains (3) summary
    cd00992
    Location:1020 → 1101
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd05609
    Location:441 → 720
    STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
    pfam08926
    Location:131 → 405
    DUF1908; Domain of unknown function (DUF1908)

  9. XM_023625475.1 → XP_023481243.1  microtubule-associated serine/threonine-protein kinase 3 isoform X6

    UniProtKB/TrEMBL
    A0A9L0R2A9
    Related
    ENSECAP00000055844.1, ENSECAT00000088493.1
    Conserved Domains (3) summary
    smart00228
    Location:956 → 1037
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd05609
    Location:377 → 656
    STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
    pfam08926
    Location:67 → 341
    DUF1908; Domain of unknown function (DUF1908)

  10. XM_023625474.1 → XP_023481242.1  microtubule-associated serine/threonine-protein kinase 3 isoform X5

    UniProtKB/TrEMBL
    A0A9L0R2A9
    Conserved Domains (3) summary
    cd00992
    Location:957 → 1038
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd05609
    Location:378 → 657
    STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
    pfam08926
    Location:68 → 342
    DUF1908; Domain of unknown function (DUF1908)

  11. XM_023625477.1 → XP_023481245.1  microtubule-associated serine/threonine-protein kinase 3 isoform X8

    UniProtKB/TrEMBL
    A0A9L0S0J4
    Conserved Domains (3) summary
    cd00992
    Location:952 → 1033
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd05609
    Location:373 → 652
    STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
    pfam08926
    Location:63 → 337
    DUF1908; Domain of unknown function (DUF1908)

  12. XM_023625476.1 → XP_023481244.1  microtubule-associated serine/threonine-protein kinase 3 isoform X7

    UniProtKB/TrEMBL
    A0A9L0S0J4, F6VT19
    Related
    ENSECAP00000006099.2, ENSECAT00000008180.4
    Conserved Domains (3) summary
    cd00992
    Location:953 → 1034
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd05609
    Location:374 → 653
    STKc_MAST; Catalytic domain of the Protein Serine/Threonine Kinase, Microtubule-associated serine/threonine kinase
    pfam08926
    Location:64 → 338
    DUF1908; Domain of unknown function (DUF1908)
Nucleotide Protein
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