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BCKDHA branched chain keto acid dehydrogenase E1 subunit alpha [ Ovis aries (sheep) ]

Gene ID: 100145857, updated on 11-Apr-2024

Summary

Gene symbol
BCKDHA
Gene description
branched chain keto acid dehydrogenase E1 subunit alpha
See related
EnsemblRapid:ENSOARG00020018183
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Ovis aries
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
Orthologs
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Genomic context

See BCKDHA in Genome Data Viewer
Location:
chromosome: 14
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 14 NC_056067.1 (50096244..50114859)

Chromosome 14 - NC_056067.1Genomic Context describing neighboring genes Neighboring gene B9 domain containing 2 Neighboring gene transmembrane protein 91 Neighboring gene exosome component 5 Neighboring gene UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8 Neighboring gene distal membrane arm assembly component 2 Neighboring gene cytochrome P450 2B11-like

Genomic regions, transcripts, and products

Genomic Sequence:
NC_056067.1 Chromosome 14 Reference ARS-UI_Ramb_v3.0 Primary Assembly

General protein information

Preferred Names
2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial
Names
branched chain keto acid dehydrogenase E1, alpha polypeptide
NP_001119816.1
XP_042086623.1
XP_060253816.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001126344.1NP_001119816.1  2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial

    See identical proteins and their annotated locations for NP_001119816.1

    Status: PROVISIONAL

    Source sequence(s)
    EU579456
    UniProtKB/TrEMBL
    A0A6P9FQE0, B2LSM3, W5PBX9
    Related
    ENSOARP00020048264.1, ENSOART00020045044.1
    Conserved Domains (1) summary
    cd02000
    Location:107399
    TPP_E1_PDC_ADC_BCADC; Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain ...

RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UI_Ramb_v3.0 Primary Assembly

Genomic

  1. NC_056067.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Range
    50096244..50114859
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_060397833.1XP_060253816.1  2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial isoform X2

  2. XM_042230689.1XP_042086623.1  2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial isoform X1

    Conserved Domains (1) summary
    cd02000
    Location:37308
    TPP_E1_PDC_ADC_BCADC; Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain ...