HEXA hexosaminidase subunit alpha [Ovis aries (sheep)] - Gene

Summary

Gene symbol: HEXA
Gene description: hexosaminidase subunit alpha
See related: EnsemblRapid:ENSOARG00020004469
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Ovis aries
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 7

Exon count:: 14

Annotation release	Status	Assembly	Chr	Location
RS_2023_10	current	ARS-UI_Ramb_v3.0 (GCF_016772045.2)	7	NC_056060.1 (19104364..19135657, complement)

Chromosome 7 - NC_056060.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_056060.1 Chromosome 7 Reference ARS-UI_Ramb_v3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables beta-N-acetylhexosaminidase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in carbohydrate metabolic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in ganglioside catabolic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in glycosaminoglycan metabolic process	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: beta-hexosaminidase subunit alpha

Names: hexosaminidase A (alpha polypeptide)

NP_001119815.1

EC 3.2.1.52

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001126343.1 → NP_001119815.1 beta-hexosaminidase subunit alpha precursor

See identical proteins and their annotated locations for NP_001119815.1

Status: PROVISIONAL

Source sequence(s)

EU579459

UniProtKB/TrEMBL

A0A6P3CWX9, B2LSM6

Related

ENSOARP00020005716.1, ENSOART00020006915.2

Conserved Domains (2) summary

cd06562
Location:167 → 511

GH20_HexA_HexB-like; Beta-N-acetylhexosaminidases catalyze the removal of beta-1,4-linked N-acetyl-D-hexosamine residues from the non-reducing ends of N-acetyl-beta-D-hexosaminides including N-acetylglucosides and N-acetylgalactosides. The hexA and hexB genes encode the ...

pfam14845
Location:23 → 145

Glycohydro_20b2; beta-acetyl hexosaminidase like