ndst3 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3 [Xenopus tropicalis (tropical clawed frog)] - Gene

Summary

Official Symbol: ndst3provided by Xenbase
Official Full Name: N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3provided by Xenbase
Primary source: Xenbase:XB-GENE-1001604
See related: Ensembl:ENSXETG00000004033 AllianceGenome:Xenbase:XB-GENE-1001604
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus tropicalis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Summary: Predicted to enable [heparan sulfate]-glucosamine N-sulfotransferase activity and deacetylase activity. Predicted to act upstream of or within heparan sulfate proteoglycan biosynthetic process and heparin biosynthetic process. Predicted to be located in membrane. Orthologous to human NDST3 (N-deacetylase and N-sulfotransferase 3). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 1

Exon count:: 14

Annotation release	Status	Assembly	Chr	Location
104	current	UCB_Xtro_10.0 (GCF_000004195.4)	1	NC_030677.2 (70273701..70393443)
103	previous assembly	Xenopus_tropicalis_v9.1 (GCF_000004195.3)	1	NC_030677.1 (60850187..60970002)

Chromosome 1 - NC_030677.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables [heparan sulfate]-glucosamine N-sulfotransferase activity	IEA Inferred from Electronic Annotation more info
enables deacetylase activity	IEA Inferred from Electronic Annotation more info
enables hydrolase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within heparan sulfate proteoglycan biosynthetic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within heparin biosynthetic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3

NP_001120519.1

EC 2.8.2.8

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001127047.1 → NP_001120519.1 bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3

See identical proteins and their annotated locations for NP_001120519.1

Status: PROVISIONAL

Source sequence(s)

BC161424

UniProtKB/TrEMBL

A0A7D9NLI9, A0A803JPF3, B1H3K2

Related

ENSXETP00000008730.5, ENSXETT00000008730.5

Conserved Domains (2) summary

pfam00685
Location:595 → 846

Sulfotransfer_1; Sulfotransferase domain

pfam12062
Location:21 → 506

HSNSD; heparan sulfate-N-deacetylase