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hdac8 histone deacetylase 8 [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 100145561, updated on 17-Aug-2024

Summary

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Official Symbol
hdac8provided by Xenbase
Official Full Name
histone deacetylase 8provided by Xenbase
Primary source
Xenbase:XB-GENE-5863426
See related
Ensembl:ENSXETG00000020527
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as
HD8
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 8
Exon count:
18
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 8 NC_030684.2 (36941767..36997132, complement)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 8 NC_030684.1 (16416020..16431318, complement)

Chromosome 8 - NC_030684.2Genomic Context describing neighboring genes Neighboring gene phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform Neighboring gene cyclin-O protein B Neighboring gene Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1 Neighboring gene cyclin-O protein B-like Neighboring gene cyclin-O protein B Neighboring gene cyclin-O protein B-like Neighboring gene cyclin-O protein B

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables histone deacetylase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables histone deacetylase activity IEA
Inferred from Electronic Annotation
more info
  
enables histone deacetylase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables histone decrotonylase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables protein decrotonylase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within chromatin organization IEA
Inferred from Electronic Annotation
more info
  
involved_in heterochromatin formation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of NuRD complex IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in chromosome IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
histone deacetylase 8
Names
protein deacetylase HDAC8
protein decrotonylase HDAC8
NP_001120462.1
XP_012823478.1
XP_012823480.1
XP_012823481.1
XP_012823482.1
XP_031746075.1
XP_031746077.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001126990.1 → NP_001120462.1  histone deacetylase 8

    See identical proteins and their annotated locations for NP_001120462.1

    Status: PROVISIONAL

    Source sequence(s)
    BC161282
    UniProtKB/Swiss-Prot
    B1H369
    UniProtKB/TrEMBL
    A0A6I8S385, A0A6I8SVP1
    Related
    ENSXETP00000091308.2, ENSXETT00000095452.2
    Conserved Domains (1) summary
    cd10000
    Location:7 → 369
    HDAC8; Histone deacetylase 8 (HDAC8)

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030684.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    36941767..36997132 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_031890215.1 → XP_031746075.1  histone deacetylase 8 isoform X1

    UniProtKB/TrEMBL
    A0A6I8PPE5, A0A6I8RNR5, A0A6I8S385, A0A6I8SRZ2, A0A6I8SVP1, A0A803K8W2
    Related
    ENSXETP00000083975.2, ENSXETT00000097138.2
    Conserved Domains (1) summary
    cd10000
    Location:1 → 338
    HDAC8; Histone deacetylase 8 (HDAC8)

  2. XM_031890217.1 → XP_031746077.1  histone deacetylase 8 isoform X2

    UniProtKB/TrEMBL
    A0A6I8S385, A0A6I8SVP1, A0A803K8W2, A0A8J0SSE5
    Conserved Domains (1) summary
    cd10000
    Location:3 → 325
    HDAC8; Histone deacetylase 8 (HDAC8)

  3. XM_012968027.3 → XP_012823481.1  histone deacetylase 8 isoform X2

    See identical proteins and their annotated locations for XP_012823481.1

    UniProtKB/TrEMBL
    A0A6I8S385, A0A6I8SVP1, A0A803K8W2, A0A8J0SSE5
    Related
    ENSXETP00000100639.1, ENSXETT00000104616.2
    Conserved Domains (1) summary
    cd10000
    Location:3 → 325
    HDAC8; Histone deacetylase 8 (HDAC8)

  4. XM_012968026.3 → XP_012823480.1  histone deacetylase 8 isoform X1

    See identical proteins and their annotated locations for XP_012823480.1

    UniProtKB/TrEMBL
    A0A6I8PPE5, A0A6I8RNR5, A0A6I8S385, A0A6I8SRZ2, A0A6I8SVP1, A0A803K8W2
    Conserved Domains (1) summary
    cd10000
    Location:1 → 338
    HDAC8; Histone deacetylase 8 (HDAC8)

  5. XM_012968028.3 → XP_012823482.1  histone deacetylase 8 isoform X2

    See identical proteins and their annotated locations for XP_012823482.1

    UniProtKB/TrEMBL
    A0A6I8S385, A0A6I8SVP1, A0A803K8W2, A0A8J0SSE5
    Conserved Domains (1) summary
    cd10000
    Location:3 → 325
    HDAC8; Histone deacetylase 8 (HDAC8)

  6. XM_012968024.3 → XP_012823478.1  histone deacetylase 8 isoform X1

    See identical proteins and their annotated locations for XP_012823478.1

    UniProtKB/TrEMBL
    A0A6I8PPE5, A0A6I8RNR5, A0A6I8S385, A0A6I8SRZ2, A0A6I8SVP1, A0A803K8W2
    Related
    ENSXETP00000044353.4, ENSXETT00000044353.5
    Conserved Domains (1) summary
    cd10000
    Location:1 → 338
    HDAC8; Histone deacetylase 8 (HDAC8)

RNA

  1. XR_001171464.2 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
B1H369.1 GenPept UniProtKB/Swiss-Prot:B1H369

Gene LinkOut

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