b4galt1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1, gene 1 [Xenopus tropicalis (tropical clawed frog)] - Gene

Summary

Official Symbol: b4galt1provided by Xenbase
Official Full Name: UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1, gene 1provided by Xenbase
Primary source: Xenbase:XB-GENE-5871724
See related: Ensembl:ENSXETG00000024147 AllianceGenome:Xenbase:XB-GENE-5871724
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus tropicalis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as: gt1; gtb; cdg2d; ggtb2; b4gal-t1; b4galt1.1; beta4gal-t1
Summary: Predicted to enable glycosyltransferase activity and metal ion binding activity. Predicted to act upstream of or within carbohydrate metabolic process and protein glycosylation. Predicted to be located in Golgi cisterna membrane and Golgi membrane. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation and congenital disorder of glycosylation type IId. Orthologous to human B4GALT1 (beta-1,4-galactosyltransferase 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 1

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
104	current	UCB_Xtro_10.0 (GCF_000004195.4)	1	NC_030677.2 (94228552..94291504)
103	previous assembly	Xenopus_tropicalis_v9.1 (GCF_000004195.3)	1	NC_030677.1 (75344988..75401727)

Chromosome 1 - NC_030677.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables glycosyltransferase activity	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within carbohydrate metabolic process	IEA Inferred from Electronic Annotation more info
involved_in protein N-linked glycosylation	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within protein glycosylation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in Golgi apparatus	IBA Inferred from Biological aspect of Ancestor more info
located_in Golgi apparatus	IEA Inferred from Electronic Annotation more info
located_in Golgi cisterna membrane	IEA Inferred from Electronic Annotation more info
located_in Golgi membrane	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1, gene 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001126960.1 → NP_001120432.1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1, gene 1

See identical proteins and their annotated locations for NP_001120432.1

Status: PROVISIONAL

Source sequence(s)

BC161189

UniProtKB/TrEMBL

B1H2Z5, F6YQV3

Conserved Domains (1) summary

cd00899
Location:130 → 347

b4GalT; Beta-4-Galactosyltransferase is involved in the formation of the poly-N-acetyllactosamine core structures present in glycoproteins and glycosphingolipids

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

NC_030677.2 Reference UCB_Xtro_10.0 Primary Assembly

Range

94228552..94291504

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_012956214.3 → XP_012811668.2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1, gene 1 isoform X1

UniProtKB/TrEMBL

A0A803JHY3, F6YQV3

Related

ENSXETP00000107547.1, ENSXETT00000111057.1

Conserved Domains (1) summary

cd00899
Location:149 → 366

b4GalT; Beta-4-Galactosyltransferase is involved in the formation of the poly-N-acetyllactosamine core structures present in glycoproteins and glycosphingolipids