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xylt1 xylosyltransferase I [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 100145490, updated on 14-Nov-2024

Summary

Official Symbol
xylt1provided by Xenbase
Official Full Name
xylosyltransferase Iprovided by Xenbase
Primary source
Xenbase:XB-GENE-949399
See related
Ensembl:ENSXETG00000019693 AllianceGenome:Xenbase:XB-GENE-949399
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Summary
Predicted to enable metal ion binding activity and protein xylosyltransferase activity. Predicted to act upstream of or within chondroitin sulfate biosynthetic process and heparan sulfate proteoglycan biosynthetic process. Predicted to be located in Golgi membrane. Human ortholog(s) of this gene implicated in Desbuquois dysplasia; pseudoxanthoma elasticum; and type 1 diabetes mellitus. Orthologous to human XYLT1 (xylosyltransferase 1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See xylt1 in Genome Data Viewer
Location:
chromosome: 9
Exon count:
11
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 9 NC_030685.2 (33097011..33285145, complement)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 9 NC_030685.1 (27221762..27408995, complement)

Chromosome 9 - NC_030685.2Genomic Context describing neighboring genes Neighboring gene ARL6 interacting reticulophagy regulator 1 Neighboring gene ribosomal protein S15a Neighboring gene uncharacterized LOC100491090 Neighboring gene NODAL modulator 3

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables protein xylosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables protein xylosyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
xylosyltransferase 1
NP_001120412.1
XP_012825540.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001126940.1NP_001120412.1  xylosyltransferase 1

    See identical proteins and their annotated locations for NP_001120412.1

    Status: PROVISIONAL

    Source sequence(s)
    BC161138
    UniProtKB/TrEMBL
    B1H2U9, F6QQR0
    Related
    ENSXETP00000042631.5, ENSXETT00000042631.5
    Conserved Domains (2) summary
    pfam02485
    Location:291543
    Branch; Core-2/I-Branching enzyme
    pfam12529
    Location:576756
    Xylo_C; Xylosyltransferase C terminal

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030685.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    33097011..33285145 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012970086.3XP_012825540.2  xylosyltransferase 1 isoform X1

    UniProtKB/TrEMBL
    A0A8J0SWU4, F6QQR0
    Conserved Domains (2) summary
    pfam12529
    Location:575755
    Xylo_C; Xylosyltransferase C terminal
    cl27418
    Location:291543
    Branch; Core-2/I-Branching enzyme