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nars2 asparaginyl-tRNA synthetase 2, mitochondrial [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 100145238, updated on 4-Nov-2024

Summary

Official Symbol
nars2provided by Xenbase
Official Full Name
asparaginyl-tRNA synthetase 2, mitochondrialprovided by Xenbase
Primary source
Xenbase:XB-GENE-944603
See related
AllianceGenome:Xenbase:XB-GENE-944603
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Summary
Predicted to enable asparagine-tRNA ligase activity. Predicted to be involved in asparaginyl-tRNA aminoacylation. Predicted to act upstream of or within translation. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 94 and combined oxidative phosphorylation deficiency 24. Orthologous to human NARS2 (asparaginyl-tRNA synthetase 2, mitochondrial). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See nars2 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
14
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 2 NC_030678.2 (169090659..169117804, complement)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 2 NC_030678.1 (165763269..165792931, complement)

Chromosome 2 - NC_030678.2Genomic Context describing neighboring genes Neighboring gene ubiquitin specific peptidase 35 Neighboring gene GRB2 associated binding protein 2 Neighboring gene teneurin transmembrane protein 4 Neighboring gene ABC transporter F family member 4-like

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables aminoacyl-tRNA ligase activity IEA
Inferred from Electronic Annotation
more info
 
enables asparagine-tRNA ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables asparagine-tRNA ligase activity IEA
Inferred from Electronic Annotation
more info
 
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in asparaginyl-tRNA aminoacylation IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within asparaginyl-tRNA aminoacylation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within translation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
probable asparagine--tRNA ligase, mitochondrial
Names
asparaginyl-tRNA synthetase 2, mitochondrial (putative)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030678.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    169090659..169117804 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_031896237.1XP_031752097.1  probable asparagine--tRNA ligase, mitochondrial

    UniProtKB/TrEMBL
    A0A8J1J2M8
    Conserved Domains (1) summary
    PRK03932
    Location:157614
    asnC; asparaginyl-tRNA synthetase; Validated