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GUSB glucuronidase beta [ Sus scrofa (pig) ]

Gene ID: 100144519, updated on 18-Sep-2024

Summary

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Official Symbol
GUSBprovided by VGNC
Official Full Name
glucuronidase betaprovided by VGNC
Primary source
VGNC:VGNC:103960
See related
Ensembl:ENSSSCG00000007739
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Expression
Broad expression in liver (RPKM 57.6), spleen (RPKM 40.4) and 8 other tissues See more
Orthologs
human mouse all
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Genomic context

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See GUSB in Genome Data Viewer
Location:
chromosome: 3
Exon count:
12
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 3 NC_010445.4 (16672071..16686520)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) 3 NC_010445.3 (16924697..16939444)

Chromosome 3 - NC_010445.4Genomic Context describing neighboring genes Neighboring gene CGRP receptor component Neighboring gene DAZ-associated protein 2 pseudogene Neighboring gene uncharacterized LOC102161858 Neighboring gene argininosuccinate lyase Neighboring gene vitamin K epoxide reductase complex subunit 1 like 1 Neighboring gene uncharacterized LOC102162776 Neighboring gene nuclear protein 2, transcriptional regulator

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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Related articles in PubMed

  1. Molecular characterization and exclusion of porcine GUSB as a candidate gene for congenital hernia inguinalis/scrotalis. Beck J, et al. BMC Vet Res, 2006 Apr 28. PMID 16646965, Free PMC Article
  2. PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences. Uenishi H, et al. Nucleic Acids Res, 2007 Jan. PMID 17145712, Free PMC Article
  3. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article
  4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables beta-glucuronidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables carbohydrate binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables signaling receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
beta-glucuronidase
NP_001116593.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001123121.1 → NP_001116593.1  beta-glucuronidase precursor

    See identical proteins and their annotated locations for NP_001116593.1

    Status: PROVISIONAL

    Source sequence(s)
    DQ095863
    UniProtKB/Swiss-Prot
    Q4FAT7
    UniProtKB/TrEMBL
    A0A8D0P4C8, A0A8D1NK41, A0A8D2CIF8
    Related
    ENSSSCP00000043718.2, ENSSSCT00000040486.3
    Conserved Domains (4) summary
    PRK10150
    Location:28 → 631
    PRK10150; beta-D-glucuronidase; Provisional
    pfam00703
    Location:226 → 327
    Glyco_hydro_2; Glycosyl hydrolases family 2
    pfam02836
    Location:329 → 631
    Glyco_hydro_2_C; Glycosyl hydrolases family 2, TIM barrel domain
    pfam02837
    Location:37 → 224
    Glyco_hydro_2_N; Glycosyl hydrolases family 2, sugar binding domain

RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010445.4 Reference Sscrofa11.1 Primary Assembly

    Range
    16672071..16686520
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q4FAT7.1 GenPept UniProtKB/Swiss-Prot:Q4FAT7

Gene LinkOut

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