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Grn granulin precursor [ Cavia porcellus (domestic guinea pig) ]

Gene ID: 100135533, updated on 3-Apr-2024

Summary

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Gene symbol
Grn
Gene description
granulin precursor
See related
Ensembl:ENSCPOG00000008789
Gene type
protein coding
RefSeq status
MODEL
Organism
Cavia porcellus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae; Cavia
Also known as
acrogranin
Orthologs
human mouse all
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Genomic context

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See Grn in Genome Data Viewer
Location:
chromosome: Un
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_02 current mCavPor4.1 (GCF_034190915.1) Unplaced Scaffold NW_026947489.1 (95422385..95427104)
103 previous assembly Cavpor3.0 (GCF_000151735.1) Unplaced Scaffold NT_176352.1 (9363120..9367763, complement)

NW_026947489.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111755609 Neighboring gene RUN domain containing 3A Neighboring gene solute carrier family 25 member 39 Neighboring gene family with sequence similarity 171 member A2 Neighboring gene integrin subunit alpha 2b Neighboring gene uncharacterized LOC134476570

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. ADAM15 participates in fertilization through a physical interaction with acrogranin. Pastén K, et al. Reproduction, 2014 Dec. PMID 25392190
  2. Acrogranin, an acrosomal cysteine-rich glycoprotein, is the precursor of the growth-modulating peptides, granulins, and epithelins, and is expressed in somatic as well as male germ cells. Baba T, et al. Mol Reprod Dev, 1993 Mar. PMID 8471244

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in regulation of inflammatory response IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
progranulin

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_034190915.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mCavPor4.1

Genomic

  1. NW_026947489.1 Reference mCavPor4.1

    Range
    95422385..95427104
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063251699.1 → XP_063107769.1  progranulin isoform X3

  2. XM_013148160.2 → XP_013003614.1  progranulin isoform X1

    Related
    ENSCPOP00000007890.3
    Conserved Domains (2) summary
    smart00277
    Location:224 → 274
    GRAN; Granulin
    pfam00396
    Location:560 → 601
    Granulin; Granulin

  3. XM_063251698.1 → XP_063107768.1  progranulin isoform X2

    UniProtKB/Swiss-Prot
    H0VD49, P28797
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P28797.2 GenPept UniProtKB/Swiss-Prot:P28797

Gene LinkOut

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